PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_12822_iso_1

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

bHLH

Protein Properties

Length: 366aa MW: 40337.5 Da PI: 4.8054

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_12822_iso_1	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	33.5	7.6e-11	189	234	5	55
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 h ++Er+RR+++ + f L ++P + kK++K ++L A+ Y+k++q cra_locus_12822_iso_1_len_1418_ver_3 189 HIIAERKRREQLSQHFVALSAIVPGL-----KKMDKTSVLGDAITYLKHMQ 234 899*********************.....9****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.068	184	233	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.03E-15	185	250	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.46E-10	189	238	No hit	No description
Gene3D	G3DSA:4.10.280.10	5.1E-15	189	247	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.8E-8	189	234	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.9E-12	190	239	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 366 aa Download sequence Send to blast
MTMMMTMDNS VNSWFSDLGM EDPFSSDQYD ITDFLNEDFA ALGEDLQAFT PTAESDSSNN 60 FINIPTSNSS NTLCALATEL PSVVAEIPTT ITATTTTKKR KSNSSTNQNV PNARRAARTP 120 IVLTFGNTTA ETNPNKHSLS PDINDDSLIS TENLTSQGNL EEAVAAAKST KLNKKTGGRV 180 RPASQTYDHI IAERKRREQL SQHFVALSAI VPGLKKMDKT SVLGDAITYL KHMQERVKTL 240 EEQTTKQTME SVVLVKKSQV LVEDEGSSDE IDQDQSSSQL PEIEAKVCDK TILLRVHCEK 300 NKRVLINILS QLEKLNLVVT NTSVSAFGSL ALDITIIVEM EKESSINMKE LIQTLRSAVM 360 RANLED

Sequence ? help Back to Top

Protein Sequence Length: 366 aa Download sequence Send to blast

MTMMMTMDNS VNSWFSDLGM EDPFSSDQYD ITDFLNEDFA ALGEDLQAFT PTAESDSSNN  60
FINIPTSNSS NTLCALATEL PSVVAEIPTT ITATTTTKKR KSNSSTNQNV PNARRAARTP  120
IVLTFGNTTA ETNPNKHSLS PDINDDSLIS TENLTSQGNL EEAVAAAKST KLNKKTGGRV  180
RPASQTYDHI IAERKRREQL SQHFVALSAI VPGLKKMDKT SVLGDAITYL KHMQERVKTL  240
EEQTTKQTME SVVLVKKSQV LVEDEGSSDE IDQDQSSSQL PEIEAKVCDK TILLRVHCEK  300
NKRVLINILS QLEKLNLVVT NTSVSAFGSL ALDITIIVEM EKESSINMKE LIQTLRSAVM  360
RANLED

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	192	197	ERKRRE

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027103298.1	1e-127	transcription factor bHLH18-like
TrEMBL	A0A0H3V2H6	0.0	A0A0H3V2H6_CATRO; BHLH iridoid synthesis 1

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1760	24	61

Publications ? help Back to Top
Van Moerkercke A, et al. The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus. Proc. Natl. Acad. Sci. U.S.A., 2015. 112(26): p. 8130-5 [PMID:26080427]