PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Zmw_sc06005.1.g00050.1

Organism

Zoysia matrella

Taxonomic ID

38722

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia

Family

bHLH

Protein Properties

Length: 373aa MW: 39854.3 Da PI: 7.7896

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Zmw_sc06005.1.g00050.1	genome	ZGD	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	28.3	3.1e-09	183	230	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR+ri +++ L+el+P + sk Ka +L + ++Y++sLq Zmw_sc06005.1.g00050.1.sm.mk 183 SHSLAERVRRERISERMRYLQELVPGC----SKVTGKAGMLDEIINYVQSLQ 230 8***********************9....556***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.96E-16	177	244	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.33E-10	177	234	No hit	No description
Gene3D	G3DSA:4.10.280.10	7.1E-16	179	241	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.491	179	229	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.7E-6	183	230	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.7E-9	185	235	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 373 aa Download sequence Send to blast
MAQCGGDLLS RILHQETVKG LLGLDDDKFG AMCSAFGYLQ EWPELSAMCG NDMAPPDAAN 60 GNDDDSCSAG GGLRKRKPDA CHDAKVRDLC SRKARASLFH KMCLLTSDSG GIVTWQGEHG 120 DGCKRPRGKQ QLSLSDRGEV AGKGKQERPK AGSKKKADAA SPAAGQKTDY IHVRARRGQA 180 TDSHSLAERV RRERISERMR YLQELVPGCS KVTGKAGMLD EIINYVQSLQ NQVEFLSMKI 240 AASNPVVSLD IVEDLFGRQL KQACNAAASS AMAVPAGQPQ PSCVQMSPMQ QMRLPAGSSG 300 FGLQMVVNSP YPPAPSGPMP AATSGSNAPC LNMNGPAAAA VWDIGSQNFF SGFDAQFQPI 360 ESDCLLDNLK MEM

Sequence ? help Back to Top

Protein Sequence Length: 373 aa Download sequence Send to blast

MAQCGGDLLS RILHQETVKG LLGLDDDKFG AMCSAFGYLQ EWPELSAMCG NDMAPPDAAN  60
GNDDDSCSAG GGLRKRKPDA CHDAKVRDLC SRKARASLFH KMCLLTSDSG GIVTWQGEHG  120
DGCKRPRGKQ QLSLSDRGEV AGKGKQERPK AGSKKKADAA SPAAGQKTDY IHVRARRGQA  180
TDSHSLAERV RRERISERMR YLQELVPGCS KVTGKAGMLD EIINYVQSLQ NQVEFLSMKI  240
AASNPVVSLD IVEDLFGRQL KQACNAAASS AMAVPAGQPQ PSCVQMSPMQ QMRLPAGSSG  300
FGLQMVVNSP YPPAPSGPMP AATSGSNAPC LNMNGPAAAA VWDIGSQNFF SGFDAQFQPI  360
ESDCLLDNLK MEM

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	72	77	LRKRKP

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds DNA to G box 5'-CACGTG-3' and, to a lower extent, to E-box 5'-CANNTG-3' in vitro. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light. {ECO:0000269\|PubMed:18988809, ECO:0000269\|PubMed:24130508}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Accumulates strongly in response to blue light due to reduced preventing 26S proteasome-mediated degradation in an ADO1/ZTL and ADO2/LKP2 dependent manner, but levels decrease in the absence of blue light via 26S proteasome degradation (at protein level). {ECO:0000269\|PubMed:24101505}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_025813679.1	1e-149	transcription factor bHLH49-like
Swissprot	Q8GY61	1e-47	BH063_ARATH; Transcription factor bHLH63
TrEMBL	A0A0A9CZD0	1e-161	A0A0A9CZD0_ARUDO; Uncharacterized protein
STRING	Si017630m	1e-140	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP8252	37	49

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Yang D,Zhao W,Meng Y,Li H,Liu B A CIB1-LIKE transcription factor GmCIL10 from soybean positively regulates plant flowering. Sci China Life Sci, 2015. 58(3): p. 261-9 [PMID:25651969] Katsura Y, et al. An optogenetic system for interrogating the temporal dynamics of Akt. Sci Rep, 2015. 5: p. 14589 [PMID:26423353] Taslimi A, et al. Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase. Nat. Chem. Biol., 2016. 12(6): p. 425-30 [PMID:27065233] Liu Q, et al. The Blue Light-Dependent Polyubiquitination and Degradation of Arabidopsis Cryptochrome2 Requires Multiple E3 Ubiquitin Ligases. Plant Cell Physiol., 2016. 57(10): p. 2175-2186 [PMID:27516416] Pathak GP, et al. Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. Nucleic Acids Res., 2017. 45(20): p. e167 [PMID:28431041] Duan L, et al. Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017. 8(1): p. 547 [PMID:28916751] Quejada JR, et al. Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1. Nucleic Acids Res., 2017. 45(20): p. e172 [PMID:29040770] Liu Y, et al. CIB1 and CO interact to mediate CRY2-dependent regulation of flowering. EMBO Rep., 2019. [PMID:30126927]