PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016469253.1

Common Name

An1b

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 686aa MW: 75862.8 Da PI: 4.989

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016469253.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	43.7	4.8e-14	486	531	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h +ErrRR+++N++f Lr+l+P +K++Ka+iL ++eY+k+L XP_016469253.1 486 NHVLAERRRREKLNERFIILRSLVPFV-----TKMDKASILGDTIEYVKQL 531 7999********************8.....8***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	1.6E-54	10	192	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	17.688	482	531	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.0E-19	486	548	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.26E-15	486	536	No hit	No description
Pfam	PF00010	1.3E-11	486	531	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.44E-18	486	546	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.9E-18	488	537	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010026	Biological Process	trichome differentiation
GO:0010214	Biological Process	seed coat development
GO:2000029	Biological Process	regulation of proanthocyanidin biosynthetic process
GO:0000976	Molecular Function	transcription regulatory region sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 686 aa Download sequence Send to blast
MTEIPPNSQM QTMLQKAVQS VQWTYTLFWQ LCSQQGVLVW RDGYYNGAIK TRKTVQPMEV 60 SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI 120 GLPGKAYSKK HHIWIMCANE VDSKVFCRAI LAKSARIQTV VCIPLLDGVL ELGTTERVQE 180 DIGFINHVKS FFTEQQQPQP PKPALSEHST SNSTTFSEPH FYSGNTPPSG NADIAQQDGG 240 AAGEEDEEEE EEEDDEAELD SDSIAIQSEV GGAANPIAAE ASELMQLDMS EAIRLGSPDD 300 GSNNMDSDFH LVGAGNTADY QRQPDSFKAE TAISWAHFQD LQHLPGGSSY EELSQEDTHY 360 SQTVSTILEH FSNRSSKFSS TTMGCISHDS AQSAFTLCPS TTVDCSPNPA HCRRRHDDSL 420 LDGGGASPSS QWLLKSILFT VPFLHTKYQS EASPKSVDVA TVDSSSTASR FRKGCSITSQ 480 EEPSGNHVLA ERRRREKLNE RFIILRSLVP FVTKMDKASI LGDTIEYVKQ LHKKVQDLEA 540 RARHTEQSKD AVTKDQKSGT ATVKVLQGRG KRRMNTVEAG NIGGGQAKMT AFPLSTTEDE 600 EVVQVEVSII ESDALLELRC PYKEGLLLDV MQMLRELKVE VVAIQSSLNN GIFLAELRAK 660 VKENIYGRKA SIVEVKKSIH QIIPRD

Sequence ? help Back to Top

Protein Sequence Length: 686 aa Download sequence Send to blast

MTEIPPNSQM QTMLQKAVQS VQWTYTLFWQ LCSQQGVLVW RDGYYNGAIK TRKTVQPMEV  60
SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI  120
GLPGKAYSKK HHIWIMCANE VDSKVFCRAI LAKSARIQTV VCIPLLDGVL ELGTTERVQE  180
DIGFINHVKS FFTEQQQPQP PKPALSEHST SNSTTFSEPH FYSGNTPPSG NADIAQQDGG  240
AAGEEDEEEE EEEDDEAELD SDSIAIQSEV GGAANPIAAE ASELMQLDMS EAIRLGSPDD  300
GSNNMDSDFH LVGAGNTADY QRQPDSFKAE TAISWAHFQD LQHLPGGSSY EELSQEDTHY  360
SQTVSTILEH FSNRSSKFSS TTMGCISHDS AQSAFTLCPS TTVDCSPNPA HCRRRHDDSL  420
LDGGGASPSS QWLLKSILFT VPFLHTKYQS EASPKSVDVA TVDSSSTASR FRKGCSITSQ  480
EEPSGNHVLA ERRRREKLNE RFIILRSLVP FVTKMDKASI LGDTIEYVKQ LHKKVQDLEA  540
RARHTEQSKD AVTKDQKSGT ATVKVLQGRG KRRMNTVEAG NIGGGQAKMT AFPLSTTEDE  600
EVVQVEVSII ESDALLELRC PYKEGLLLDV MQMLRELKVE VVAIQSSLNN GIFLAELRAK  660
VKENIYGRKA SIVEVKKSIH QIIPRD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	7e-20	10	192	9	192	Transcription factor MYC3
4rqw_B	7e-20	10	192	9	192	Transcription factor MYC3
4rs9_A	7e-20	10	192	9	192	Transcription factor MYC3
4yz6_A	7e-20	10	192	9	192	Transcription factor MYC3
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	490	495	ERRRRE
2	491	496	RRRREK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the control of flavonoid pigmentation. {ECO:0000269\|PubMed:20949001}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HQ589209	0.0	HQ589209.1 Nicotiana tabacum anthocyanin 1b (An1b) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016469253.1	0.0	PREDICTED: basic helix-loop-helix protein A-like isoform X1
Swissprot	E3SXU4	0.0	BHLHW_PEA; Basic helix-loop-helix protein A
TrEMBL	A0A1S3ZY28	0.0	A0A1S3ZY28_TOBAC; basic helix-loop-helix protein A-like isoform X1
STRING	XP_009602346.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA9028	20	22

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G09820.1	2e-95	bHLH family protein

Publications ? help Back to Top
Hellens RP, et al. Identification of Mendel's white flower character. PLoS ONE, 2010. 5(10): p. e13230 [PMID:20949001] Bai Y, et al. Flavonoid-related basic helix-loop-helix regulators, NtAn1a and NtAn1b, of tobacco have originated from two ancestors and are functionally active. Planta, 2011. 234(2): p. 363-75 [PMID:21484270]