PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016446601.1

Common Name

An1a

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 671aa MW: 74106.8 Da PI: 4.9798

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016446601.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	43.8	4.6e-14	475	521	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h +ErrRR+++N++f Lr+l+P +K++Ka+iL ++eY+k+L+ XP_016446601.1 475 NHVLAERRRREKLNERFIILRSLVPFV-----TKMDKASILGDTIEYVKQLR 521 7999********************8.....8***************95 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	4.6E-52	11	192	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	17.688	471	520	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	8.07E-16	475	525	No hit	No description
Pfam	PF00010	1.3E-11	475	520	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.53E-18	475	532	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.7E-19	475	536	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.3E-18	477	526	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 671 aa Download sequence Send to blast
MTEIPPNSQM KTMLQKAVQS VQWTYTLFWQ LCPQQGALVW RDGYYNGAIK TRKTVQPMEV 60 SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI 120 GLPGKAYSKK HHIWIMGANE VDSKVFCRAI LAKSARIQTV VGIPLLDGVL ELGTTERVQE 180 EIGFINHVKS FFTEQQQPQL PKPALSEHST SNPTTFSEPH FYSGNTSPSA NVDIAHQDGG 240 AAGEEDEEEE EEEDDDEAEL DSDSIAIQSA ANPIAVEASE LMQLDVSEAI QLGSPDDDSD 300 NMDSDFHLVG AGNTAHDYQR QADSFKAETA ISWPHFQDLQ QLPGGSSYDE LSQEDTHYSQ 360 TVSTILEHRS SKFSSTTMGC ISHDSAQSAF TLCPSTTVCS PNPAHCRHDD SLVDGGGASQ 420 WLLKSILFTV PFLHTKYQSE ASPKSRDVAT VDSSSTASRF RKGCSITSQE EPSGNHVLAE 480 RRRREKLNER FIILRSLVPF VTKMDKASIL GDTIEYVKQL RKKVQDLEAR ARDTEHSRDA 540 DKKGGTATVK VLQGRGKRRM NTVDGSVGGG QATITASPPS TTENEEVVQV QVSIIESDAL 600 VELRCPYKEG LLLNVMQMLR ELKVEVVAIQ SALNNGVFLA ELRAKVKENI CGRKASILEV 660 KRSIHQIIPR D

Sequence ? help Back to Top

Protein Sequence Length: 671 aa Download sequence Send to blast

MTEIPPNSQM KTMLQKAVQS VQWTYTLFWQ LCPQQGALVW RDGYYNGAIK TRKTVQPMEV  60
SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI  120
GLPGKAYSKK HHIWIMGANE VDSKVFCRAI LAKSARIQTV VGIPLLDGVL ELGTTERVQE  180
EIGFINHVKS FFTEQQQPQL PKPALSEHST SNPTTFSEPH FYSGNTSPSA NVDIAHQDGG  240
AAGEEDEEEE EEEDDDEAEL DSDSIAIQSA ANPIAVEASE LMQLDVSEAI QLGSPDDDSD  300
NMDSDFHLVG AGNTAHDYQR QADSFKAETA ISWPHFQDLQ QLPGGSSYDE LSQEDTHYSQ  360
TVSTILEHRS SKFSSTTMGC ISHDSAQSAF TLCPSTTVCS PNPAHCRHDD SLVDGGGASQ  420
WLLKSILFTV PFLHTKYQSE ASPKSRDVAT VDSSSTASRF RKGCSITSQE EPSGNHVLAE  480
RRRREKLNER FIILRSLVPF VTKMDKASIL GDTIEYVKQL RKKVQDLEAR ARDTEHSRDA  540
DKKGGTATVK VLQGRGKRRM NTVDGSVGGG QATITASPPS TTENEEVVQV QVSIIESDAL  600
VELRCPYKEG LLLNVMQMLR ELKVEVVAIQ SALNNGVFLA ELRAKVKENI CGRKASILEV  660
KRSIHQIIPR D

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	1e-17	10	192	9	192	Transcription factor MYC3
4rqw_B	1e-17	10	192	9	192	Transcription factor MYC3
4rs9_A	1e-17	10	192	9	192	Transcription factor MYC3
4yz6_A	1e-17	10	192	9	192	Transcription factor MYC3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	479	484	ERRRRE
2	480	485	RRRREK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the control of flavonoid pigmentation. {ECO:0000269\|PubMed:20949001}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HQ589208	0.0	HQ589208.1 Nicotiana tabacum anthocyanin 1a (An1a) mRNA, complete cds.
GenBank	HQ589210	0.0	HQ589210.1 Nicotiana sylvestris anthocyanin 1-like protein (An1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001312042.1	0.0	basic helix-loop-helix protein A-like
Swissprot	E3SXU4	0.0	BHLHW_PEA; Basic helix-loop-helix protein A
TrEMBL	A0A1S3Y397	0.0	A0A1S3Y397_TOBAC; basic helix-loop-helix protein A-like
STRING	XP_009803795.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA9028	20	22

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G09820.1	2e-94	bHLH family protein

Publications ? help Back to Top
Hellens RP, et al. Identification of Mendel's white flower character. PLoS ONE, 2010. 5(10): p. e13230 [PMID:20949001] Bai Y, et al. Flavonoid-related basic helix-loop-helix regulators, NtAn1a and NtAn1b, of tobacco have originated from two ancestors and are functionally active. Planta, 2011. 234(2): p. 363-75 [PMID:21484270]