PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016446208.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

NAC

Protein Properties

Length: 293aa MW: 34227.2 Da PI: 5.1065

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016446208.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	153.6	9.1e-48	22	147	2	128
NAM 2 ppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk 95 ppG+rF P+d+el+v+yLkkkv +++l+ + ikev+++ + P++L + +ekewyfF++rdkky++g+r+nra+ +gyWkatg dk++ + XP_016446208.1 22 PPGYRFCPRDDELIVHYLKKKVMNEPLPS-NEIKEVNLCMHSPQQLSeTYPVVGEKEWYFFTPRDKKYKNGTRPNRAAGTGYWKATGADKPINH- 114 9*************************9.67**********8334445899**********************************. PP NAM 96 kgelvglkktLvfykgrapkgektdWvmheyrl 128 +g+ vg +k Lv+y+g+ +kg+kt+W+mheyr+ XP_016446208.1 115 NGAIVGFRKALVYYQGEPQKGKKTNWIMHEYRV 147 999**************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.31E-55	17	173	IPR003441	NAC domain
PROSITE profile	PS51005	52.761	21	173	IPR003441	NAC domain
Pfam	PF02365	2.0E-26	22	147	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 293 aa Download sequence Send to blast
MESDRQIQAN FKVDDYDSLA FPPGYRFCPR DDELIVHYLK KKVMNEPLPS NEIKEVNLCM 60 HSPQQLSETY PVVGEKEWYF FTPRDKKYKN GTRPNRAAGT GYWKATGADK PINHNGAIVG 120 FRKALVYYQG EPQKGKKTNW IMHEYRVNES RVEKKDGNTW RLDSWVLCRI YQKVDKSLKT 180 IRRELNSPLS INDHVGMDCD YEGTTDSIGT DNTFEENVQL LDIAYNSSDI PVDSSIKKFA 240 KLNVDYGYPF QGDEANFNMA QENFTWSYFT YDYMNDVQWD FPSWQENSLL PLD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	8e-52	14	173	8	168	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that positively regulates age-dependent senescence, dark-induced leaf senescence and stress-induced senescence. Regulates leaf senescence through the modulation of the expression of senescence-associated genes SGR1/NYE1, SAG113 and SAUR36/SAG201, which are involved in chlorophyll degradation, and abscisic acid (ABA) and auxin promotion of senescence, respectively. Promotes reactive oxygen species (ROS) production during age-dependent and stress-induced senescence. Regulates positively auxin-mediated responses in roots (PubMed:27388337). Stress-responsive NAC transcription factor involved in ABA-inducible leaf senescence signaling (PubMed:26518251). Required for normal seed development and morphology (PubMed:18849494). {ECO:0000269\|PubMed:18849494, ECO:0000269\|PubMed:26518251, ECO:0000269\|PubMed:27388337}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA) (PubMed:26518251). Induced by salinity and osmotic stress, and during leaf senescence (PubMed:27388337). {ECO:0000269\|PubMed:26518251, ECO:0000269\|PubMed:27388337}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016446208.1	0.0	PREDICTED: NAC transcription factor 29-like
Swissprot	Q9CAR0	1e-56	NAC32_ARATH; NAC transcription factor 32
TrEMBL	A0A1S3Y1V7	0.0	A0A1S3Y1V7_TOBAC; NAC transcription factor 29-like
STRING	XP_009769770.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA746	24	103

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G77450.1	5e-59	NAC domain containing protein 32

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Takasaki H, et al. SNAC-As, stress-responsive NAC transcription factors, mediate ABA-inducible leaf senescence. Plant J., 2015. 84(6): p. 1114-23 [PMID:26518251] Mahmood K,El-Kereamy A,Kim SH,Nambara E,Rothstein SJ ANAC032 Positively Regulates Age-Dependent and Stress-Induced Senescence in Arabidopsis thaliana. Plant Cell Physiol., 2016. 57(10): p. 2029-2046 [PMID:27388337] Allu AD,Brotman Y,Xue GP,Balazadeh S Transcription factor ANAC032 modulates JA/SA signalling in response to Pseudomonas syringae infection. EMBO Rep., 2016. 17(11): p. 1578-1589 [PMID:27632992] Mahmood K,Xu Z,El-Kereamy A,Casaretto JA,Rothstein SJ The Arabidopsis Transcription Factor ANAC032 Represses Anthocyanin Biosynthesis in Response to High Sucrose and Oxidative and Abiotic Stresses. Front Plant Sci, 2016. 7: p. 1548 [PMID:27790239] Song L, et al. A transcription factor hierarchy defines an environmental stress response network. Science, 2017. [PMID:27811239]