PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_013626025.1
Organism
Brassica oleracea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family GRF
Protein Properties Length: 364aa    MW: 39981.4 Da    PI: 8.5968
Description GRF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_013626025.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRC72.64.6e-23137173137
             WRC   1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrs 37 
                     d+epgrCrRtDGKkWRCsr+v +g+k+CErH+hr+r+
  XP_013626025.1 137 DPEPGRCRRTDGKKWRCSRDVFAGHKYCERHMHRSRK 173
                     79*********************************97 PP
2QLQ53.85.9e-1972108137
             QLQ   1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 
                     s F++aQ+q+L+ Q+l+y+y++a++ vP+eLl++i+k
  XP_013626025.1  72 SFFSWAQWQELELQALIYRYMLAGAAVPQELLLPIKK 108
                     67*********************************86 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM009515.3E-1272108IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166620.24773108IPR014978Glutamine-Leucine-Glutamine, QLQ
PfamPF088806.2E-1374106IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166723.146137182IPR014977WRC domain
PfamPF088793.8E-19138173IPR014977WRC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0006995Biological Processcellular response to nitrogen starvation
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0009624Biological Processresponse to nematode
GO:0009631Biological Processcold acclimation
GO:0016036Biological Processcellular response to phosphate starvation
GO:0048364Biological Processroot development
GO:0048366Biological Processleaf development
GO:0050826Biological Processresponse to freezing
GO:0051365Biological Processcellular response to potassium ion starvation
GO:0061062Biological Processregulation of nematode larval development
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0005524Molecular FunctionATP binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 364 aa     Download sequence    Send to blast
MDLQLKQWRS QQVQTESEPQ PSAAKIPRHA FDPIQSQTAT STVLPLFASE PASSKLSSLC  60
PDSSSRFSKM GSFFSWAQWQ ELELQALIYR YMLAGAAVPQ ELLLPIKKSL LHLSPSYFLQ  120
HLPHYQPAWY LGRGAMDPEP GRCRRTDGKK WRCSRDVFAG HKYCERHMHR SRKPVETPTV  180
NATTTTSMAA PPTAAPSSTP SAFAFGGGQE VGQRGSSSFF FSSQSCSEMK QESNNNKRPY  240
ESHNGFGSNG SDGGHILRHF FDDWPRSEAG NTSSPMSSAT CLSISMPVNS SSDVSLKLST  300
GNEEEARSNN IGRDQQNMSW WSGGGTNHNH HHMGGPLAEA LRSSSSSSPT SVLHQLGVST  360
QAFH
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during the early stages of leaf development and expression decreases with the maturation of the leaf. {ECO:0000269|PubMed:20023165}.
UniprotTISSUE SPECIFICITY: Strongly expressed in actively growing and developing tissues, such as roots, upper stems, and shoot tips containing the shoot apical meristem (SAM) and flower buds. Also expressed in mature flowers, but weakly expressed in mature stems and leaves. {ECO:0000269|PubMed:12974814}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium. {ECO:0000269|PubMed:12974814, ECO:0000269|PubMed:22419826}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_013626025.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). Up-regulated in response to cyst nematode infection. {ECO:0000269|PubMed:15200956, ECO:0000269|PubMed:19453503, ECO:0000269|PubMed:20023165, ECO:0000269|PubMed:22419826}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1174171e-153AK117417.1 Arabidopsis thaliana At2g36400 mRNA for unknown protein, complete cds, clone: RAFL17-02-B13.
GenBankAY1026361e-153AY102636.1 Arabidopsis thaliana transcription activator (GRF3) mRNA, complete cds.
GenBankBT0264721e-153BT026472.1 Arabidopsis thaliana At2g36400 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013626025.10.0PREDICTED: growth-regulating factor 3-like isoform X1
SwissprotQ9SJR51e-177GRF3_ARATH; Growth-regulating factor 3
TrEMBLA0A0D3B5820.0A0A0D3B582_BRAOL; Uncharacterized protein
TrEMBLA0A3P6AA860.0A0A3P6AA86_BRAOL; Uncharacterized protein (Fragment)
STRINGBo3g030090.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM19262667
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G52910.12e-98growth-regulating factor 4
Publications ? help Back to Top
  1. Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P
    Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves.
    Plant Cell, 2013. 25(9): p. 3570-83
    [PMID:24076976]
  2. Vercruyssen L, et al.
    ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development.
    Plant Cell, 2014. 26(1): p. 210-29
    [PMID:24443518]
  3. Liu J,Rice JH,Chen N,Baum TJ,Hewezi T
    Synchronization of developmental processes and defense signaling by growth regulating transcription factors.
    PLoS ONE, 2014. 9(5): p. e98477
    [PMID:24875638]
  4. Cao Y,Han Y,Jin Q,Lin Y,Cai Y
    Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa).
    Front Plant Sci, 2016. 7: p. 1750
    [PMID:27933074]