PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Moraceae; Morus

Family

HSF

Protein Properties

Length: 476aa MW: 53058.8 Da PI: 5.2876

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010097956.1	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	112.1	3.9e-35	22	112	2	101
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellek 96 Fl k+y++++d++++e++sws+n+nsfvv+++ ef++ +Lp+yFkh+nf+SF+RQLn+YgF+k++ e+ weF+++ F k++k+ll++ XP_010097956.1 22 FLLKTYDMVDDSATDEIVSWSSNKNSFVVWNPPEFSRLLLPTYFKHNNFSSFIRQLNTYGFRKIDPER---------WEFANEDFVKDQKHLLKN 107 9**************************************************************999.........************** PP XXXXX CS HSF_DNA-bind 97 ikrkk 101 i+r+k XP_010097956.1 108 IHRRK 112 *98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46785	2.86E-35	18	111	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	8.0E-38	18	111	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	1.1E-59	18	111	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	6.6E-19	22	45	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	6.5E-31	22	111	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	6.6E-19	60	72	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	61	85	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	6.6E-19	73	85	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 476 aa Download sequence Send to blast
MEAAHAGGGG GGGGGSGGPA PFLLKTYDMV DDSATDEIVS WSSNKNSFVV WNPPEFSRLL 60 LPTYFKHNNF SSFIRQLNTY GFRKIDPERW EFANEDFVKD QKHLLKNIHR RKPIHSHSNP 120 QCSLVDPERA ALDEEIEKLS REKLVLEANI ARCKQQLTAK HQLENVTQRV NGIERRQDNL 180 QSFLEKAVQD PAFIDYVIER IESMDLAYNK KRRLPEVDYS QPAVDDSFVE NQSNSRAEFG 240 NIFHRDFSNK LRLELSPAVS DINPVSNSNQ SSNEEGETTQ KKISEGELRG TRTRTEGLFL 300 APEPLELSDT GTSFGFKMDS SLSIKPPTSG SPRLHSLQPN LTSCEEGDSR ISCQLNLTLA 360 SLPSQVNNIP YSAGMLSESR FVANTKESDI VATPKKKNLA DEGKPLSAPQ EAANNQAAAV 420 KVNDVFWEQF LTERPGCSDN EEASSNYRTS TYDEQSDGRL GHGISKNAKN VEQLTL

Sequence ? help Back to Top

Protein Sequence Length: 476 aa Download sequence Send to blast

MEAAHAGGGG GGGGGSGGPA PFLLKTYDMV DDSATDEIVS WSSNKNSFVV WNPPEFSRLL  60
LPTYFKHNNF SSFIRQLNTY GFRKIDPERW EFANEDFVKD QKHLLKNIHR RKPIHSHSNP  120
QCSLVDPERA ALDEEIEKLS REKLVLEANI ARCKQQLTAK HQLENVTQRV NGIERRQDNL  180
QSFLEKAVQD PAFIDYVIER IESMDLAYNK KRRLPEVDYS QPAVDDSFVE NQSNSRAEFG  240
NIFHRDFSNK LRLELSPAVS DINPVSNSNQ SSNEEGETTQ KKISEGELRG TRTRTEGLFL  300
APEPLELSDT GTSFGFKMDS SLSIKPPTSG SPRLHSLQPN LTSCEEGDSR ISCQLNLTLA  360
SLPSQVNNIP YSAGMLSESR FVANTKESDI VATPKKKNLA DEGKPLSAPQ EAANNQAAAV  420
KVNDVFWEQF LTERPGCSDN EEASSNYRTS TYDEQSDGRL GHGISKNAKN VEQLTL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	9e-22	9	111	17	129	Heat shock factor protein 1
5d5v_B	9e-22	9	111	17	129	Heat shock factor protein 1
5d5v_D	9e-22	9	111	17	129	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010097956.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KR132193	1e-116	KR132193.1 Eriobotrya japonica heat shock factor 2 (HSF2) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010097956.1	0.0	heat stress transcription factor A-5
Swissprot	Q94BZ5	1e-160	HSFA5_ARATH; Heat stress transcription factor A-5
TrEMBL	W9RUK3	0.0	W9RUK3_9ROSA; Heat stress transcription factor A-5
STRING	XP_010097956.1	0.0	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4961	32	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G13980.1	1e-154	HSF family protein

Link Out ? help Back to Top
Entrez Gene	21409489

Publications ? help Back to Top
Reňák D,Gibalová A,Solcová K,Honys D A new link between stress response and nucleolar function during pollen development in Arabidopsis mediated by AtREN1 protein. Plant Cell Environ., 2014. 37(3): p. 670-83 [PMID:23961845]