PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

ERF

Protein Properties

Length: 210aa MW: 23961.8 Da PI: 8.2062

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009798818.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	56.8	5.5e-18	103	153	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpseng.krkrfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+++AeIr p k +r +lg++ t+e+Aa a+++a+ k++g XP_009798818.1 103 RYRGVRRRP-WGKFAAEIRNP---DrKGARLWLGTYETPEDAALAYDQAAYKIRG 153 7******.******8...3245***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	9.15E-23	103	162	IPR016177	DNA-binding domain
SMART	SM00380	1.8E-35	103	167	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.302	103	161	IPR001471	AP2/ERF domain
CDD	cd00018	3.41E-30	103	163	No hit	No description
Gene3D	G3DSA:3.30.730.10	1.2E-31	103	162	IPR001471	AP2/ERF domain
Pfam	PF00847	1.0E-13	103	153	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.6E-13	104	115	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.6E-13	143	163	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 210 aa Download sequence Send to blast
MYEQTTISDS DLSVLENIKF HLLNDNDFSQ IYSTFDQCFS NAEIINSPDS SFGSSPTEEI 60 SWGDMLTSVN TTWQRVDNLE YKEETKKNHV VARGVHAPQD WNRYRGVRRR PWGKFAAEIR 120 NPDRKGARLW LGTYETPEDA ALAYDQAAYK IRGSKARLNF PHLIGSNISE PVRVAPRRRC 180 LSPEISSSSF SLSFVENVPL KKRKLEGNIG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	4e-27	104	161	3	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269\|PubMed:11950980}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Strongly induced by wounding. Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Also induced by methyl jasmonate (MeJA) independently of JAR1, but seems to not be affected by ethylene. Induction by salicylic acid (SA) is controlled by growth and/or developmental conditions, and seems to be more efficient and independent of PAD4 in older plants. {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12068110}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB828153	0.0	AB828153.1 Nicotiana tabacum ERF91 mRNA for ethylene response factor 91, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009798817.1	1e-157	PREDICTED: ethylene-responsive transcription factor 2-like isoform X1
Refseq	XP_009798818.1	1e-157	PREDICTED: ethylene-responsive transcription factor 2-like isoform X2
Swissprot	Q8L9K1	6e-44	ERF99_ARATH; Ethylene-responsive transcription factor 13
TrEMBL	A0A1U7Y6R6	1e-155	A0A1U7Y6R6_NICSY; ethylene-responsive transcription factor 2-like isoform X1
STRING	XP_009798818.1	1e-156	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G44840.1	1e-45	ethylene-responsive element binding factor 13

Publications ? help Back to Top
Maimbo M,Ohnishi K,Hikichi Y,Yoshioka H,Kiba A Induction of a small heat shock protein and its functional roles in Nicotiana plants in the defense response against Ralstonia solanacearum. Plant Physiol., 2007. 145(4): p. 1588-99 [PMID:17965181] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]