PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

ERF

Protein Properties

Length: 168aa MW: 19078.5 Da PI: 5.4069

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009624601.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	61.8	1.6e-19	35	86	2	56
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkklege 56 +y GVr ++ +g+++AeIrd ++ng +r++lg+f+taeeAa +++a+ +++g+ XP_009624601.1 35 HYIGVRKRP-WGKFAAEIRDSTSNG--RRVWLGTFDTAEEAAMTYDQAAFCMRGP 86 799****.******66687..************************95 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	8.97E-31	34	92	No hit	No description
Gene3D	G3DSA:3.30.730.10	1.5E-29	35	93	IPR001471	AP2/ERF domain
Pfam	PF00847	2.1E-14	35	85	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.58E-22	35	94	IPR016177	DNA-binding domain
SMART	SM00380	1.6E-34	35	99	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	21.443	35	93	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.8E-9	36	47	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.8E-9	59	75	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 168 aa Download sequence Send to blast
MDLKIQDHET LISIKVEVES LSLETNDSIS KEEKHYIGVR KRPWGKFAAE IRDSTSNGRR 60 VWLGTFDTAE EAAMTYDQAA FCMRGPSTCL NFSVEKVRES LQKMECNNLK EGLLSPAAAL 120 KEKHKKRSSS SRKKQVNIIK EEENVFIFED LGPDLLDELL SEYSSSSN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	7e-27	34	95	1	62	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A	7e-27	34	95	4	65	ATERF1
3gcc_A	7e-27	34	95	4	65	ATERF1
5wx9_A	1e-26	24	95	3	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	122	133	KHKKRSSSSRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975450	1e-107	HG975450.1 Solanum pennellii chromosome ch11, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009624601.1	1e-122	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	2e-43	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A1U7YSG1	1e-114	A0A1U7YSG1_NICSY; ethylene-responsive transcription factor 15-like
STRING	XP_009624601.1	1e-121	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G31230.1	9e-40	ethylene-responsive element binding factor 15

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]