PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

ERF

Protein Properties

Length: 262aa MW: 30010.4 Da PI: 5.3021

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009619700.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	61.1	2.4e-19	136	186	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y GVr ++ +g+++AeIrd + ng r++lg+f+taeeAa a+++a+ +++g XP_009619700.1 136 HYIGVRKRP-WGKYAAEIRDSTRNG--IRVWLGTFDTAEEAALAYDQAAFSMRG 186 799****.******44465..***********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	7.12E-29	135	194	No hit	No description
Pfam	PF00847	1.2E-13	136	186	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.9E-29	136	195	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	21.799	136	194	IPR001471	AP2/ERF domain
SMART	SM00380	4.7E-36	136	200	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.37E-22	136	195	IPR016177	DNA-binding domain
PRINTS	PR00367	9.7E-10	137	148	IPR001471	AP2/ERF domain
PRINTS	PR00367	9.7E-10	160	176	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 262 aa Download sequence Send to blast
MEISSLDQFP NFDFLQDQFP WEFEYSELIN DHVDQIPRSS SFSETNSSKG SSEEGFEEDR 60 TGHPSHHPKE VERGERIPSF SRRGQVSIFD QMPKSSSSSE TNSLKGSSAD EEVTSYSIKR 120 KDADADKKEL QDEEKHYIGV RKRPWGKYAA EIRDSTRNGI RVWLGTFDTA EEAALAYDQA 180 AFSMRGPLAF LNFPMEKVQE SLQKIEMNCN QLLDGLSPAA ALKETHKMRM KNVKRRRNRK 240 KKNAVLVFED LGTDLLEELL MS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	9e-28	124	196	2	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009619700.1	0.0	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	4e-51	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A1U7YC10	1e-139	A0A1U7YC10_NICSY; ethylene-responsive transcription factor 1B-like
STRING	XP_009619700.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G31230.1	3e-32	ethylene-responsive element binding factor 15

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]