PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

ERF

Protein Properties

Length: 234aa MW: 26973.9 Da PI: 5.1122

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009609579.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	62.1	1.2e-19	99	149	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y GVr ++ +g+++AeIrd + ng r++lg+f+taeeAa a+++a+++++g XP_009609579.1 99 HYIGVRKRP-WGKYAAEIRDSTRNG--IRVWLGTFDTAEEAALAYDQAALSMRG 149 799****.******44465..***********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00380	1.1E-33	99	163	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	7.2E-29	99	158	IPR001471	AP2/ERF domain
Pfam	PF00847	8.4E-14	99	149	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	21.799	99	157	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	3.07E-22	99	158	IPR016177	DNA-binding domain
CDD	cd00018	8.66E-28	99	157	No hit	No description
PRINTS	PR00367	8.1E-10	100	111	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.1E-10	123	139	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 234 aa Download sequence Send to blast
MSSNSSPLEI DTSFSHSNFF FLQDQSPILQ WDDDLFFNDP WFDDDQSPII PCNSEKDENH 60 QVFEESSDNT IMSKGSSHGQ ELEEVTSQEE KEKEEEEKHY IGVRKRPWGK YAAEIRDSTR 120 NGIRVWLGTF DTAEEAALAY DQAALSMRGP WSLLNFPLEK VKKSLEKIEY SCKDGLSPAA 180 VLKATHKTRR VKHKRSSRKK KNKETHNVIV FEDLGAELLE ELLMTSSQHS CRRD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	3e-28	98	158	1	61	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY655738	0.0	AY655738.1 Nicotiana tabacum ERF transcription factor 5 (ERF5) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001313204.1	1e-175	ethylene-responsive transcription factor 1B-like
Refseq	XP_009609579.1	1e-175	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	2e-49	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	Q5Y836	1e-174	Q5Y836_TOBAC; ERF transcription factor 5
STRING	XP_009609579.1	1e-174	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	7e-30	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]