PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009593924.1
Organism
Nicotiana tomentosiformis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family ERF
Protein Properties Length: 309aa    MW: 34711.3 Da    PI: 4.6211
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009593924.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP257.53.3e-182776255
             AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                    ++ GVr+++ +grWvAeI+d +   ++ r +lg+f taeeAa+a+++a+  l+g
  XP_009593924.1 27 KFVGVRQRP-SGRWVAEIKDTT---QKIRMWLGTFETAEEAARAYDQAACLLRG 76
                    799******.7*********32...35**********************99987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008477.0E-132776IPR001471AP2/ERF domain
SuperFamilySSF541713.01E-192785IPR016177DNA-binding domain
CDDcd000182.53E-312783No hitNo description
Gene3DG3DSA:3.30.730.101.2E-272784IPR001471AP2/ERF domain
PROSITE profilePS5103219.5462784IPR001471AP2/ERF domain
SMARTSM003803.6E-352790IPR001471AP2/ERF domain
PRINTSPR003671.1E-72839IPR001471AP2/ERF domain
PRINTSPR003671.1E-75066IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 309 aa     Download sequence    Send to blast
MEINFQKQQQ KEAKVTKLKG GNNRSNKFVG VRQRPSGRWV AEIKDTTQKI RMWLGTFETA  60
EEAARAYDQA ACLLRGSNTR TNFVTRVSVD SPLASRIKNL LNSKKTAKPS SHDQKEQSSA  120
SSTTSSHNIN QNTSSVTSNN SNNSSPMIST SYFDDSISSQ NIEPIHLLEN AALADDYMSY  180
DQITLSCNQE LQLQESQLFD DTYKPDLSNC SDEFDVGYSS SSASNSFSFT NSSQLEMSWN  240
FAQELLDHPK NVVLDETTEM GLVEFERMKM ERSISASLYA VNGVQEYIEN FYDPSEPLWD  300
LPPLCSLLC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A2e-152488267ATERF1
3gcc_A2e-152488267ATERF1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs) (PubMed:17449807, PubMed:17827349). Binds to the GCC-box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation and maintenance, and nodule development. Necessary for NF-induced gene expression and spontaneous nodulation activated by CCAMK. Functions downstream of CCAMK to activate nodulation gene expression (PubMed:17449807). Involved in early stages of root nodule development. Functions redundantly with ERN2. Is essential with ERN2 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241, ECO:0000269|PubMed:27208242}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in roots from 1 to 21 day after inoculation with Sinorhizobium meliloti (PubMed:17449807). Induced by Nod factors in root hairs (PubMed:17827349). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC2378755e-57AC237875.1 Solanum tuberosum cultivar RH89-039-16 clone RH168B16, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009593924.10.0PREDICTED: ethylene-responsive transcription factor RAP2-11-like
SwissprotA2Q5W18e-85ERN1_MEDTR; Ethylene-responsive transcription factor ERN1
TrEMBLA0A1S3ZNJ60.0A0A1S3ZNJ6_TOBAC; ethylene-responsive transcription factor RAP2-11-like
STRINGXP_009593924.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA20182261
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G19790.11e-29related to AP2 11
Publications ? help Back to Top
  1. Cerri MR, et al.
    Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
    Plant Physiol., 2012. 160(4): p. 2155-72
    [PMID:23077241]
  2. Tang H, et al.
    An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
    BMC Genomics, 2014. 15: p. 312
    [PMID:24767513]
  3. Cerri MR, et al.
    The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection.
    Plant Physiol., 2016. 171(2): p. 1037-54
    [PMID:27208242]