PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Traes_2BL_1E7B7A8CA.1
Organism
Triticum aestivum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum
Family E2F/DP
Protein Properties Length: 457aa    MW: 49750 Da    PI: 5.0025
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Traes_2BL_1E7B7A8CA.1genomeIWGSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP79.72.6e-25145210171
                E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                            r e+sL+ lt+kf++ll+++e+gi++ln+va+ L    v  k+RRiYDi+NVLe+++l+ekk kn+irw+g
  Traes_2BL_1E7B7A8CA.1 145 RAEHSLGELTKKFISLLKQAEDGILDLNNVAEIL---VV--KKRRIYDITNVLEGIGLLEKKLKNRIRWRG 210
                            6799******************************...88..9***************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.2E-27143212IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.8E-30145210IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.58E-16145208IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023193.2E-23147210IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.57E-42220326No hitNo description
SuperFamilySSF1440742.22E-30221326No hitNo description
PfamPF164212.1E-29225324IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 457 aa     Download sequence    Send to blast
MSGGGRPQAA QQIVQSVQKC VPLAPERPPF AVPAEYHRFP LPPSSSAPAA ASRGSAGGDV  60
EEGIVIRTPL KRKAPCGESD AIESTEWMIT SPGFTEGVSS PHMTPISGKA ARTYKSKAKG  120
SKDGLQTPIS NAGSPGTPLT PGSSRAEHSL GELTKKFISL LKQAEDGILD LNNVAEILVV  180
KKRRIYDITN VLEGIGLLEK KLKNRIRWRG LDDSGANLDN EISVLETELE NLKLQEKALD  240
NRISEMHEKV RELTEEENNQ RWLYLTEDDI KGLPCFQNET LIAIKAPHGT TLEVPDPDEA  300
GDYIQRRYTI VIRSTMGSID LYLVSKFEEN MEELVGVATP PRHANVAEPA STDGFIATEA  360
GQSSRSKDKL PNIQHIHRTP DLNAQVGGMA KITPEFDVDA DYYLLTDGDA SSITDMWRTA  420
PEVQWDQFLA EEATAPRTPQ QHPAVVGKST AVGPTCG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A7e-23135211274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3724420.0AK372442.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv3002B23.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020167678.10.0transcription factor E2FA-like isoform X1
SwissprotQ9FNY01e-116E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A3B6C7740.0A0A3B6C774_WHEAT; Uncharacterized protein
STRINGTraes_2BL_1E7B7A8CA.10.0(Triticum aestivum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-111E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]
  2. Brenchley R, et al.
    Analysis of the bread wheat genome using whole-genome shotgun sequencing.
    Nature, 2012. 491(7426): p. 705-10
    [PMID:23192148]