PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Tp57577_TGAC_v2_mRNA1845
Organism
Trifolium pratense
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Trifolium
Family C2H2
Protein Properties Length: 503aa    MW: 55961.9 Da    PI: 6.2881
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Tp57577_TGAC_v2_mRNA1845genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H221.18.3e-07251272223
                               EETTTTEEESSHHHHHHHHHHT CS
                   zf-C2H2   2 kCpdCgksFsrksnLkrHirtH 23 
                                C++Cgk F+r  nL+ H+r H
  Tp57577_TGAC_v2_mRNA1845 251 FCTICGKGFKRDANLRMHMRGH 272
                               6*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.14E-5248275No hitNo description
PROSITE profilePS5015712.03250277IPR007087Zinc finger, C2H2
SMARTSM003550.0026250272IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.3E-5251301IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280252272IPR007087Zinc finger, C2H2
SMARTSM0035550299332IPR015880Zinc finger, C2H2-like
SMARTSM0035536337359IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010044Biological Processresponse to aluminum ion
GO:0010447Biological Processresponse to acidic pH
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 503 aa     Download sequence    Send to blast
MNPTGSLCAN NWARSSSLVP PGNGLPTNLS LDPSSFFGVG IETPFKEINQ PSPTQCVIPG  60
ESKKDVKITD QETSKLQDWD PSAMLNNLSF LEEKIHQLQD VVHMIVNKKF QPFEQPRELV  120
TQEQQLITAD LTSIIVQLIS TAGSLLPSVR NTVANTSPLI GQLSQLRGIN LPFGTGTSSG  180
IQPQNNCENK LFDHSIQNDV PNKCEMEQNH NMEEHEHKDE EDMEEGENLP PGSYEILQLE  240
KEEILAPHTH FCTICGKGFK RDANLRMHMR GHGDEYKTPA ALAKPHKETG SEPKLIKRYS  300
CPYGGCKRNK DHKKFQPLKT ILCVKNHYKR THCDKSYTCS RCHTKKFSVI ADLKTHEKHC  360
GKDKWLCSCG TTFSRKDKLF GHIALFQGHT PAIPLEENKG LAEPPDRCDA KENSTMVGSM  420
NFCFGSNPSS ENGIDNMMDV KGNIDDPINY FSSLNFEGCN FGAFNEFSQP PFEDSDSSFS  480
FLMSGSFNYA PKSGGESCSD NL*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269|PubMed:17535918, ECO:0000269|PubMed:18826429, ECO:0000269|PubMed:19321711, ECO:0000269|PubMed:23935008}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00196ampDAPTransfer from AT1G34370Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapTp57577_TGAC_v2_mRNA1845
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269|PubMed:17535918}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKC4306210.0KC430621.1 Medicago sativa sensitive to proton rhizotoxicity 1 protein (STOP1) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004496356.10.0protein SENSITIVE TO PROTON RHIZOTOXICITY 1
SwissprotQ9C8N50.0STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBLA0A2K3P1610.0A0A2K3P161_TRIPR; Protein sensitive to proton rhizotoxicity 1-like
STRINGXP_004496356.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF53403254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G34370.21e-162C2H2 family protein
Publications ? help Back to Top
  1. Kobayashi Y, et al.
    Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions.
    Plant Physiol., 2013. 163(1): p. 180-92
    [PMID:23839867]
  2. Yokosho K,Yamaji N,Ma JF
    Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench).
    Plant Cell Physiol., 2014. 55(12): p. 2077-91
    [PMID:25273892]
  3. Geng X, et al.
    LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.
    Plant J., 2017. 90(3): p. 491-504
    [PMID:28181322]
  4. Balzergue C, et al.
    Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation.
    Nat Commun, 2017. 8: p. 15300
    [PMID:28504266]
  5. Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A
    Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation.
    Front Plant Sci, 2017. 8: p. 822
    [PMID:28567051]
  6. Jiang F, et al.
    Identification and characterization of suppressor mutants of stop1.
    BMC Plant Biol., 2017. 17(1): p. 128
    [PMID:28738784]
  7. Daspute AA, et al.
    Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
    Front Plant Sci, 2017. 8: p. 1358
    [PMID:28848571]
  8. Sharma A,Wai CM,Ming R,Yu Q
    Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis.
    Genome Biol Evol, 2017. 9(9): p. 2170-2190
    [PMID:28922793]
  9. Zhang Y, et al.
    The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 118
    [PMID:29491872]