PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_06172.1_g00002.1
Organism
Solanum melongena
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family HD-ZIP
Protein Properties Length: 666aa    MW: 72747.1 Da    PI: 6.3429
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_06172.1_g00002.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox61.21.6e-193489156
                             TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
                 Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                             +++ +++t++q+++Le+ F+++++p++++r +L++ lgL  rq+k+WFqNrR+++k
  Sme2.5_06172.1_g00002.1 34 KKRYHRHTANQIQRLEAIFKECPHPDEKTRLQLSRDLGLAPRQIKFWFQNRRTQMK 89
                             678899***********************************************998 PP
2START86.36.9e-28310398119206
                              TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXX CS
                    START 119 gagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrq 203
                              ++g+w++vdvS d +q+++ ss + ++++lpSg+li++++ng+skvtwvehv+++++   h l+r l++sgla+ga +w  tlqr 
  Sme2.5_06172.1_g00002.1 310 EQGSWAVVDVSYDITQENQYSSTSCKVHRLPSGCLIQDMPNGYSKVTWVEHVEVEEKGLiHRLYRDLIHSGLAFGAERWIGTLQRV 395
                              68****************99**********************************987555************************** PP

                              XXX CS
                    START 204 cek 206
                              ce+
  Sme2.5_06172.1_g00002.1 396 CER 398
                              *97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466899.61E-201591IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.609.1E-222493IPR009057Homeodomain-like
PROSITE profilePS5007117.3783191IPR001356Homeobox domain
SMARTSM003891.0E-183295IPR001356Homeobox domain
CDDcd000861.86E-183392No hitNo description
PfamPF000463.4E-173489IPR001356Homeobox domain
PROSITE patternPS0002706689IPR017970Homeobox, conserved site
PROSITE profilePS5084812.107222251IPR002913START domain
CDDcd088754.22E-69226397No hitNo description
SuperFamilySSF559613.07E-15229399No hitNo description
SMARTSM002343.9E-6231398IPR002913START domain
PROSITE profilePS5084822.08256401IPR002913START domain
PfamPF018527.2E-23310398IPR002913START domain
SuperFamilySSF559614.85E-20419642No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 666 aa     Download sequence    Send to blast
MEYAGTGGGG GGGTSSGGGG CADPHDASDP HRRKKRYHRH TANQIQRLEA IFKECPHPDE  60
KTRLQLSRDL GLAPRQIKFW FQNRRTQMKA QHERADNCAL RAENDKIRCE NIAIREALKH  120
VICPSCGGPP VNEDSYFDEQ KLRIENMQLK EELDKVSSIA AKYIGRPISQ LPPVQPIHLS  180
SLDLSMSSFI GHGPNSLDLD LDLLPGSSSS MPNLAYATLN LSDMDKSLMA DIAGNAMEEL  240
IRLVQTNEPL WMKSTIDGRD VLNFDNYDRV FPGANSHLKN PNVRIEASRD SGVVIMNGLA  300
LVDVFMDAIE QGSWAVVDVS YDITQENQYS STSCKVHRLP SGCLIQDMPN GYSKVTWVEH  360
VEVEEKGLIH RLYRDLIHSG LAFGAERWIG TLQRVCERYA CLMVNSTPSH DLGGVIPSPD  420
GKRSMMKLAQ RMVSNFCASV NPSNGHQWNT ISGLNEFDVR ATLQKSTDPG QPNGVIISAA  480
ATIWLPIPPQ HVFSFFRDER TRPQWDVLSN QNPVQEVAHI VNGSHSGNCI SVLRAYNTSQ  540
NNMLILQESC IDSSGALVVY SPVDIPAINI AMSGEDPTYI PLLPSGFTIS PDGRQLDTEA  600
ASCSSSSNAG IIGGGRSGGS LITVVFQILV SSSPSAKMSP ESVNTVNNLI GSTVHQIKSA  660
LNCSTS
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that acts as negative regulator of trichome branching in association with HDG11 (PubMed:16778018). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). Acts as positive regulator of SCL18/LAS expression (PubMed:25358340). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:25358340, ECO:0000269|PubMed:25564655}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754420.0HG975442.1 Solanum pennellii chromosome ch03, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019225984.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9LMT80.0HDG12_ARATH; Homeobox-leucine zipper protein HDG12
TrEMBLA0A3Q7FQC60.0A0A3Q7FQC6_SOLLC; Uncharacterized protein
STRINGXP_006441353.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G17920.10.0homeodomain GLABROUS 12
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Tian C, et al.
    An organ boundary-enriched gene regulatory network uncovers regulatory hierarchies underlying axillary meristem initiation.
    Mol. Syst. Biol., 2014. 10: p. 755
    [PMID:25358340]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]