PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

ERF

Protein Properties

Length: 231aa MW: 26487.4 Da PI: 6.1027

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sme2.5_00211.1_g00009.1	genome	EGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	60.1	5.2e-19	103	153	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y GVr ++ +g++++eIrd + ng r++lg+f+taeeAa a+++a+++++g Sme2.5_00211.1_g00009.1 103 HYIGVRKRP-WGKYASEIRDSTRNG--IRVWLGTFDTAEEAALAYDQAALSMRG 153 799****.******44465..***********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	7.24E-28	102	162	No hit	No description
Gene3D	G3DSA:3.30.730.10	1.2E-28	103	162	IPR001471	AP2/ERF domain
SMART	SM00380	2.4E-33	103	167	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	21.456	103	161	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	8.5E-22	103	163	IPR016177	DNA-binding domain
Pfam	PF00847	6.6E-13	103	153	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.0E-10	104	115	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.0E-10	127	143	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 231 aa Download sequence Send to blast
MSSNSIPLEI DTSFAHSNFF FFQNESPPTT PWNSDDLFFN DPFVEEYDHQ DSPIINIPCE 60 NDHQEVVESS NTTTTTTSKA SGQNSHHDQE KVTSQEKKQE EKHYIGVRKR PWGKYASEIR 120 DSTRNGIRVW LGTFDTAEEA ALAYDQAALS MRGPWSLLNF PIEQVKKSLE KIEYSCKDGL 180 SPAAVLKATH KTRRVKHKRR RRKNNNKNVE NVLVFEDLGV ELLEELLINS S

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	7e-28	102	162	1	61	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	197	202	KRRRRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY044236	1e-165	AY044236.1 Lycopersicon esculentum ethylene-responsive factor 1 (ERF1) mRNA, complete cds.
GenBank	EU395634	1e-165	EU395634.1 Solanum lycopersicum ethylene response factor (ERF1) gene, promoter region and complete cds.
GenBank	HG975517	1e-165	HG975517.1 Solanum lycopersicum chromosome ch05, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006360378.1	1e-116	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	8e-50	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	M1B5Y7	1e-115	M1B5Y7_SOLTU; Uncharacterized protein
STRING	PGSC0003DMT400037826	1e-115	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	3e-30	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]