PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Sevir.7G308600.1.p | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria
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Family | E2F/DP | ||||||||
Protein Properties | Length: 443aa MW: 48383.3 Da PI: 4.4855 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 83.3 | 2e-26 | 130 | 195 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kfl+ll+ ++ giv+ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg Sevir.7G308600.1.p 130 RYDSSLGLLTKKFLNLLKGAPGGIVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 195 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 8.5E-28 | 128 | 196 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.77E-16 | 130 | 193 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 8.6E-35 | 130 | 195 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.7E-23 | 132 | 195 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 8.40E-50 | 206 | 312 | No hit | No description |
SuperFamily | SSF144074 | 5.49E-34 | 207 | 312 | No hit | No description |
Pfam | PF16421 | 2.4E-34 | 211 | 310 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 443 aa Download sequence Send to blast |
MAAAAGGAAG EARARALLQR HQPFAPPPGE YHNFGAPADA GEEVVEAVVL RTPLKRKHNR 60 EGNEAAESND WMMSPGYANA GSSPVPTPPS GKGLKPSAKP KATKGQKPCP QTPLNFGSPG 120 NPSTPVGGCR YDSSLGLLTK KFLNLLKGAP GGIVDLNNAA ETLEVQKRRI YDITNVLEGI 180 GLIEKKLKNN IRWKGIDDSR PGEVSDDMSI LQADIEALTL QEQNLDERIN EMRDRLRELT 240 EDENNQKWLY VTDDDIKSLP CFQNQTLIAI KAPHGTTLEV PDPDEVNDYP QRRYRIVLRS 300 TMGPIDVYLV SQFEEMSGME TPPRPTPTIS MDSLENPRTP LAAECSKSAG IEPNIQEGFT 360 LPPDAPSSSQ DNGGMMKIVP SELDTDADYW LLSDTGVSIT DMWKTAPDVE WDGIEKFNAE 420 DFLEVSTPRQ QDKPADVVDP RV* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 3e-23 | 119 | 196 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00661 | PBM | Transfer from Pp3c1_6880 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Sevir.7G308600.1.p |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | BT034349 | 0.0 | BT034349.1 Zea mays full-length cDNA clone ZM_BFc0009D23 mRNA, complete cds. | |||
GenBank | BT064435 | 0.0 | BT064435.1 Zea mays full-length cDNA clone ZM_BFc0168K16 mRNA, complete cds. | |||
GenBank | EU973980 | 0.0 | EU973980.1 Zea mays clone 425487 transcription factor E2F2 mRNA, complete cds. | |||
GenBank | JX469970 | 0.0 | JX469970.1 Zea mays subsp. mays clone UT3233 E2F-DP-type transcription factor mRNA, partial cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_004977340.1 | 0.0 | transcription factor E2FA isoform X1 | ||||
Swissprot | Q9FNY0 | 1e-119 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | K3Y7D1 | 0.0 | K3Y7D1_SETIT; Uncharacterized protein | ||||
STRING | Si010044m | 0.0 | (Setaria italica) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Monocots | OGMP625 | 37 | 148 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-109 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
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Phytozome | Sevir.7G308600.1.p |
Publications ? help Back to Top | |||
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