PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00022271-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family C2H2
Protein Properties Length: 392aa    MW: 43555 Da    PI: 9.5985
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00022271-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H218.45.9e-065274123
                           EEETTTTEEESSHHHHHHHHHHT CS
                zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                           ++C+ Cgk F r  nL+ H r H
  SMil_00022271-RA_Salv 52 FVCEVCGKGFQRDQNLQLHRRGH 74
                           89*******************88 PP
2zf-C2H211.80.00072128150123
                            EEETTTTEEESSHHHHHHHHHHT CS
                zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                            +kC +C k++  +s+ k H +t+
  SMil_00022271-RA_Salv 128 WKCDKCAKRYAVQSDWKAHAKTC 150
                            58******************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.93E-65174No hitNo description
Gene3DG3DSA:3.30.160.607.7E-65274IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.6355274IPR007087Zinc finger, C2H2
SMARTSM003550.0145274IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002805474IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.608.8E-4116149IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.93E-6123148No hitNo description
SMARTSM00355210128148IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010150Biological Processleaf senescence
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0048510Biological Processregulation of timing of transition from vegetative to reproductive phase
GO:0048573Biological Processphotoperiodism, flowering
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 392 aa     Download sequence    Send to blast
MTDNESTIST QNPLNTGSNP PPKKKRNLPG TPDPEAEVIA LSPKTLMATN RFVCEVCGKG  60
FQRDQNLQLH RRGHNLPWKL KQRSSKEVRK RVYVCPEKAC VHHHPSRALG DLTGIKKHFC  120
RKHGQKNWKC DKCAKRYAVQ SDWKAHAKTC GTREYKCDCG TIFSRRDSFI THRAFCDALA  180
QESLRVRGAT HTHARNLNYE FQGMPQHIHS TGMPQDLHPP FATNPSFSNL PPSTFYNLNW  240
DFTHNSSPIP LTNHKEATIS SLFSTHQNQT TNHQAEASAR MSATALLQKA AQIGATTTTH  300
PAMILGSFGL NGAVQDGNRL CGLYSTSSVT SGFGSDVESS VNENSAMNGH PQMYPSSKRR  360
RLQSHDEMAE GGETRDFLGV GICHPPSING WI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C2e-33124186365Zinc finger protein JACKDAW
5b3h_F2e-33124186365Zinc finger protein JACKDAW
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1357361KRRRL
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the DNA sequence 5'-CTTTTGTCC-3' (PubMed:21265895, PubMed:25929516). Regulates photoperiodic flowering by modulating sugar transport and metabolism (PubMed:21265895, PubMed:25929516). Regulates SUS1 and SUS4 (PubMed:21265895). Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:25829440). {ECO:0000269|PubMed:21265895, ECO:0000269|PubMed:25829440, ECO:0000269|PubMed:25929516}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by 'SHORT-ROOT' (SHR)(PubMed:16640459). Strongly down-regulated by sugar deprivation, but not regulated by day-length. {ECO:0000269|PubMed:16640459}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011100239.11e-175zinc finger protein NUTCRACKER
SwissprotQ9FFH31e-133IDD8_ARATH; Zinc finger protein NUTCRACKER
TrEMBLA0A4D9B1430.0A0A4D9B143_SALSN; Uncharacterized protein
STRINGMigut.M00153.1.p1e-168(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10324350
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G44160.11e-135C2H2-like zinc finger protein
Publications ? help Back to Top
  1. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]
  2. Long Y, et al.
    In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots.
    Nature, 2017. 548(7665): p. 97-102
    [PMID:28746306]