PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00002346-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

C2H2

Protein Properties

Length: 363aa MW: 40764.8 Da PI: 9.2467

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00002346-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.6	9.5e-05	8	28	3	23
ETTTTEEESSHHHHHHHHHHT CS zf-C2H2 3 CpdCgksFsrksnLkrHirtH 23 C++C+k F r nL+ H r H SMil_00002346-RA_Salv 8 CEICNKGFQRDQNLQLHRRGH 28 *******************88 PP
2	zf-C2H2	12.4	0.00047	82	104	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k + +s+ k H + + SMil_00002346-RA_Salv 82 WKCEKCSKKYAVQSDWKAHSKIC 104 58*****************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.6E-5	5	28	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.51E-7	5	28	No hit	No description
SMART	SM00355	0.11	6	28	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.824	6	28	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	8	28	IPR007087	Zinc finger, C2H2
SMART	SM00355	100	47	77	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	3.3E-5	70	103	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.51E-7	77	102	No hit	No description
SMART	SM00355	140	82	102	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 363 aa Download sequence Send to blast
MATNRFLCEI CNKGFQRDQN LQLHRRGHNL PWKLKQRSNK EVKKKVYICP EKSCVHHEAS 60 RALGDLTGIK KHYSRKHGEK KWKCEKCSKK YAVQSDWKAH SKICGTREYK CDCGTLFSRK 120 DSFITHRAFC DALAEESARF SSPVASANLN FRNELINTLQ TSGNPQFPML GNLDNMQKPR 180 LPLWLDSANP HLPTANSNNF TLPELVQNQW YGGRDPNQVG VGFINNMNAS SSAIPRVLKE 240 EEENKGNLSE AITSLYYTSN NHSQHETNHM SMSATALLQK AAQMGSTRAT DSSFSAAGFG 300 LISSSFSAGN FKPENLMAAE GSLTRDFLGV GGNDQNRQFM PENELAKFAT GMDMSHNHYS 360 RNE

Sequence ? help Back to Top

Protein Sequence Length: 363 aa Download sequence Send to blast

MATNRFLCEI CNKGFQRDQN LQLHRRGHNL PWKLKQRSNK EVKKKVYICP EKSCVHHEAS  60
RALGDLTGIK KHYSRKHGEK KWKCEKCSKK YAVQSDWKAH SKICGTREYK CDCGTLFSRK  120
DSFITHRAFC DALAEESARF SSPVASANLN FRNELINTLQ TSGNPQFPML GNLDNMQKPR  180
LPLWLDSANP HLPTANSNNF TLPELVQNQW YGGRDPNQVG VGFINNMNAS SSAIPRVLKE  240
EEENKGNLSE AITSLYYTSN NHSQHETNHM SMSATALLQK AAQMGSTRAT DSSFSAAGFG  300
LISSSFSAGN FKPENLMAAE GSLTRDFLGV GGNDQNRQFM PENELAKFAT GMDMSHNHYS  360
RNE

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-37	78	142	3	67	Zinc finger protein JACKDAW
5b3h_F	2e-37	78	142	3	67	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011089318.1	1e-172	protein indeterminate-domain 9
Swissprot	Q9SCQ6	1e-98	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A4D9ARF5	0.0	A0A4D9ARF5_SALSN; Uncharacterized protein
STRING	VIT_06s0004g03070.t01	1e-139	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA103	24	350

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	6e-89	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]