PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Potri.016G072300.1
Organism
Populus trichocarpa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus
Family E2F/DP
Protein Properties Length: 463aa    MW: 51112.6 Da    PI: 5.8919
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Potri.016G072300.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP80.61.3e-25138202170
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwk 70 
                         r+++sL+llt++f++l++++++gi++ln +a++L   +v  ++RRiYDi+NVLe+++liek+ kn+irwk
  Potri.016G072300.1 138 RYDSSLGLLTKRFVDLFKNADDGILDLNIAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWK 202
                         6899******************************...99..****************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.107.5E-27135202IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467856.53E-17138201IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013726.5E-33138203IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.2E-23140202IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF164216.9E-32248347IPR032198E2F transcription factor, CC-MB domain
SuperFamilySSF1440746.28E-30248349No hitNo description
CDDcd146601.71E-46248349No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 463 aa     Download sequence    Send to blast
MSGGAKASTR PAATAPPSGS ILPPLARHLA FATMKPPFLP PDDYHRFSSP STSRVAADRD  60
AEAIVVRSPR LKRKSGLADN GVSSSNHVSS PGCSNISNSP FRTPASAKGG RTYNNSKTSK  120
GNGAGPQTPV SKAAGSCRYD SSLGLLTKRF VDLFKNADDG ILDLNIAAET LEVQKRRIYD  180
ITNVLEGIGL IEKTLKNRIR WKHPKHMGTR VRINLIEWLT RGIDASRPRQ VEGDATLLQE  240
VYLVLLFMQE EIEKLTMEEH KLDDQIREMQ ERLRDMSEEE NNQKWLFVTE EDIKSLPCFL  300
NETLIAIKAP HGTTLEVLDP DEAVDCPQRR YRIILRSSMG PIDVYLVSQF EEMNSVDASA  360
FPHTSSSASH GNPVTEMTTG VRTEKRADPL AQQAPTTFSD PNATQDLGGM MKIVPSDINN  420
DSDYWLLSDA DISITDMWKT DSNIEWTDFG VADVPTPRTQ TL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-22138202772PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Pth.24330.0bud| stem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}.
UniprotTISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPotri.016G072300.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024443173.10.0transcription factor E2FA isoform X2
SwissprotQ9FNY01e-148E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2K1XC380.0A0A2K1XC38_POPTR; Uncharacterized protein
STRINGPOPTR_0016s07310.10.0(Populus trichocarpa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Representative plantOGRP12251749
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.31e-150E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]