PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Pbr025174.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
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Family | AP2 | ||||||||
Protein Properties | Length: 534aa MW: 58719.1 Da PI: 7.2828 | ||||||||
Description | AP2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | AP2 | 53.3 | 6.9e-17 | 180 | 229 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g Pbr025174.1 180 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 229 78*******************......55************************997 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Pfam | PF00847 | 6.3E-9 | 180 | 229 | IPR001471 | AP2/ERF domain |
SuperFamily | SSF54171 | 1.11E-15 | 180 | 238 | IPR016177 | DNA-binding domain |
Gene3D | G3DSA:3.30.730.10 | 6.1E-17 | 181 | 237 | IPR001471 | AP2/ERF domain |
CDD | cd00018 | 6.73E-11 | 181 | 236 | No hit | No description |
PROSITE profile | PS51032 | 17.701 | 181 | 237 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 7.5E-32 | 181 | 243 | IPR001471 | AP2/ERF domain |
CDD | cd00018 | 3.56E-12 | 272 | 317 | No hit | No description |
SuperFamily | SSF54171 | 1.96E-6 | 272 | 317 | IPR016177 | DNA-binding domain |
SMART | SM00380 | 6.0E-12 | 273 | 321 | IPR001471 | AP2/ERF domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 534 aa Download sequence Send to blast |
MWDLNDSPDQ RPRGEESEGC SSQRTSADGD EEKRKRVGSV SNSSSSAVVI EEGGSDEEED 60 QDDGPTKLAK KQGGGGGKIF GFSVAHEESM DDDPPATVTR QFFPVELDSS SSSNLDVMGP 120 AGGGGSIPPP PTSSSFPRAH WVGVNFGQSD SGSLGNQPPA GEASQQPMKK SRRGPRSRSS 180 QYRGVTFYRR TGRWESHIWD CGKQVYLGGF DTAHAAARAY DRAAIKFRGV EADINFSIED 240 YEEDLKQMRN LTKEEFVHVL RRQSTGFPRG SSKYRGVTLH KCGRWEARMG QFLGKKAYDK 300 AAIKCNGKEA VTNFDPSIYD NELNSSESSG VNAADHNLDL SLGSTNSKKN NQALGNDHHS 360 QNVAMQHQHS VPMQLDADWR SQGLRPKLNI QRDRSRDDID AQRRDGYLES EAMQLLLRTN 420 LQSQAPAEIH KYGQFSRRPT AGDIQMSRNF PPNFNSSNYH HIQFPSSSEG GGRIGSDLSL 480 STSDHQQQWQ SATPTSNLFA TAAASSGFPP QIRPSPTQNS WLQKNGFHSL TRR* |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269|PubMed:1675158, ECO:0000269|PubMed:23034631, ECO:0000269|PubMed:7919989}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Pbr025174.1 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269|PubMed:12805630, ECO:0000269|PubMed:12893888, ECO:0000269|PubMed:14555699}. |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | GU732464 | 0.0 | GU732464.1 Malus x domestica AP2 domain class transcription factor (AP2D40) mRNA, complete cds. | |||
GenBank | GU983666 | 0.0 | GU983666.1 Malus x domestica apetala 2-like protein mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | NP_001280879.1 | 0.0 | floral homeotic protein APETALA 2 | ||||
Swissprot | P47927 | 1e-111 | AP2_ARATH; Floral homeotic protein APETALA 2 | ||||
TrEMBL | Q8VWW8 | 0.0 | Q8VWW8_MALDO; Transcription factor AHAP2 | ||||
STRING | XP_008382290.1 | 0.0 | (Malus domestica) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF3784 | 34 | 63 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT4G36920.2 | 1e-100 | AP2 family protein |