PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | PK02403.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis
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Family | AP2 | ||||||||
Protein Properties | Length: 552aa MW: 61897.1 Da PI: 6.8383 | ||||||||
Description | AP2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | AP2 | 53.2 | 7.2e-17 | 184 | 233 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g PK02403.1 184 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 233 78*******************......55************************997 PP | |||||||
2 | AP2 | 43.6 | 7.2e-14 | 276 | 326 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+ +k grW+A+ + +k+++lg f+t+ eAa+a+++a+ k +g PK02403.1 276 SKYRGVTLHK-CGRWEARMGQF--L-GKKYVYLGLFDTEIEAARAYDKAAIKCNG 326 89********.7******5553..2.26**********99**********99776 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Pfam | PF00847 | 6.6E-9 | 184 | 233 | IPR001471 | AP2/ERF domain |
SuperFamily | SSF54171 | 1.9E-15 | 184 | 241 | IPR016177 | DNA-binding domain |
Gene3D | G3DSA:3.30.730.10 | 5.6E-17 | 185 | 241 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 17.701 | 185 | 241 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 7.4E-32 | 185 | 247 | IPR001471 | AP2/ERF domain |
CDD | cd00018 | 4.21E-11 | 185 | 240 | No hit | No description |
Pfam | PF00847 | 1.5E-9 | 276 | 326 | IPR001471 | AP2/ERF domain |
SuperFamily | SSF54171 | 4.9E-17 | 276 | 336 | IPR016177 | DNA-binding domain |
CDD | cd00018 | 3.65E-25 | 276 | 336 | No hit | No description |
Gene3D | G3DSA:3.30.730.10 | 2.9E-16 | 277 | 334 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 2.1E-31 | 277 | 340 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 15.659 | 277 | 334 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 7.2E-6 | 278 | 289 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 7.2E-6 | 316 | 336 | IPR001471 | AP2/ERF domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0010073 | Biological Process | meristem maintenance | ||||
GO:0010093 | Biological Process | specification of floral organ identity | ||||
GO:0048316 | Biological Process | seed development | ||||
GO:0048481 | Biological Process | plant ovule development | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 552 aa Download sequence Send to blast |
MWDLNDCPDQ RRDDESEGCS SQKTSVDGDD EKGKRVGSVS NSSSSAVVIE DGSDEEYGMG 60 TRSNMMMMMK KRSGSNSKIF GFSVTHNELE EEEEDFSMET DPSPVTRNFF PVEESEMGPS 120 SSILVGGPTD VGGGNIVDGF PRAAWVGVKF CQSDSLGPGP VKPSSMEVSQ PMKKSRRGPR 180 SRSSQYRGVT FYRRTGRWES HIWDCGKQVY LGGFDTAHAA ARAYDRAAIK FRGVEADINF 240 SLVDYEEDLK QMSNLTKEEF VHVLRRQSTG FPRGSSKYRG VTLHKCGRWE ARMGQFLGKK 300 YVYLGLFDTE IEAARAYDKA AIKCNGKDAV TNFDPSIYDN ELNSPVENSS PGNSSSNLGD 360 HNLDLSLGNA NIIKQNNYVT TSATHHGLIM DHQPNSMPFE TDWRNPGFRP KVNSGDHAMM 420 MRRDGYQLEN ETMQLLSRTH LQPPSNYNHN NNNNNNNQIM RRPGVDHQHH HHHQNHNPIQ 480 IHPINYPPNH HLHHQQQQHH HHNNSQFPSS SNMGGRNNNN NNNHGSGDPM AVQLFPTTAC 540 NCCSIIRIPT AD |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269|PubMed:1675158, ECO:0000269|PubMed:23034631, ECO:0000269|PubMed:7919989}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269|PubMed:12805630, ECO:0000269|PubMed:12893888, ECO:0000269|PubMed:14555699}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_010109804.1 | 0.0 | floral homeotic protein APETALA 2 | ||||
Swissprot | P47927 | 1e-126 | AP2_ARATH; Floral homeotic protein APETALA 2 | ||||
TrEMBL | A0A2P5B2H3 | 0.0 | A0A2P5B2H3_PARAD; AP2/ERF transcription factor | ||||
STRING | XP_010109804.1 | 0.0 | (Morus notabilis) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF3784 | 34 | 63 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT4G36920.2 | 1e-117 | AP2 family protein |