PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PDK_30s927281g003

Organism

Phoenix dactylifera

Taxonomic ID

42345

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Arecales; Arecaceae; Coryphoideae; Phoeniceae; Phoenix

Family

E2F/DP

Protein Properties

Length: 460aa MW: 51566.1 Da PI: 5.0629

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PDK_30s927281g003	genome	PDK	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	81.5	7.1e-26	83	147	1	70
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwk 70 r+++sL+llt+kf++ll+++++gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i wk PDK_30s927281g003 83 RYDNSLGLLTKKFINLLKRAQDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRICWK 147 689*****************************...99..*************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.1E-26	81	147	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	3.9E-17	83	146	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	3.0E-31	83	148	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	2.3E-23	85	147	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	4.80E-30	171	265	No hit	No description
SuperFamily	SSF144074	5.75E-20	173	262	No hit	No description
Pfam	PF16421	7.8E-18	202	262	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 460 aa Download sequence Send to blast
MEIMLKQKLK QENTEAAKSS EWTTSPGCAE MIIRPLQTPV SAKGGRACGR LKVAKYNKSG 60 PQTLVSNAGY PSGNPVTPVG TCRYDNSLGL LTKKFINLLK RAQDGILDLN KAAETLEVQK 120 RRIYDITNVL EGIGLIEKKL KNRICWKWQI NKEYFDRGLD DSRPAEIDDA VSSLQVEVES 180 LSMKDHNLEN YIRLILIPSL KLIRFCSEMQ QKLRDFCEDE NNQKWLYVTE DDIKGIPCFK 240 NETLIAIKAP HGTTLEVPDP DEVGRGMEGL IEGILRVSEY LFIYDYFLSQ FEEKFEELSG 300 MVVPPSLPPI SNSRPAETAA STTVTEGCRG KVLEVQDPRR MCTYLNSSQD LVGGMMKIVP 360 SDVDIDADYW LLSDADVSIT DMWGTSRILF LVLACSFFFS LCSQKIRSWK SLKPITAEVP 420 WDLGGRFDAN FMLGSTSIPW PQTPSSSVAE VLPSGNSTQR

Sequence ? help Back to Top

Protein Sequence Length: 460 aa Download sequence Send to blast

MEIMLKQKLK QENTEAAKSS EWTTSPGCAE MIIRPLQTPV SAKGGRACGR LKVAKYNKSG  60
PQTLVSNAGY PSGNPVTPVG TCRYDNSLGL LTKKFINLLK RAQDGILDLN KAAETLEVQK  120
RRIYDITNVL EGIGLIEKKL KNRICWKWQI NKEYFDRGLD DSRPAEIDDA VSSLQVEVES  180
LSMKDHNLEN YIRLILIPSL KLIRFCSEMQ QKLRDFCEDE NNQKWLYVTE DDIKGIPCFK  240
NETLIAIKAP HGTTLEVPDP DEVGRGMEGL IEGILRVSEY LFIYDYFLSQ FEEKFEELSG  300
MVVPPSLPPI SNSRPAETAA STTVTEGCRG KVLEVQDPRR MCTYLNSSQD LVGGMMKIVP  360
SDVDIDADYW LLSDADVSIT DMWGTSRILF LVLACSFFFS LCSQKIRSWK SLKPITAEVP  420
WDLGGRFDAN FMLGSTSIPW PQTPSSSVAE VLPSGNSTQR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	3e-23	78	147	1	72	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008809833.1	0.0	transcription factor E2FB-like isoform X1
Swissprot	Q9FV71	1e-101	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A2H3Z837	0.0	A0A2H3Z837_PHODC; transcription factor E2FB-like isoform X1
STRING	XP_008809833.1	0.0	(Phoenix dactylifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP625	37	148

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	1e-97	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]