PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ote100261350041
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Ocimeae; Ocimum
Family B3
Protein Properties Length: 663aa    MW: 72652.9 Da    PI: 7.8635
Description B3 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ote100261350041genomeOteDB-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B341.62.2e-13309390179
                                   EEEE-..-HHHHTT-EE--HHH.HTT....---..--SEEEEEETTS-EEEEEE....EEETTEEEE-TTHHHHHHHHT-- CS
                            B3   1 ffkvltpsdvlksgrlvlpkkfaeeh....ggkkeesktltledesgrsWevkliy..rkksgryvltkGWkeFvkangLk 75 
                                   f+kvl+ sd+++ grlvlpk +ae++    +  + e++ ++++d  g +W++++++  +++s++yvl+ G +   +  +++
  Ote100261350041|100261350041 309 FEKVLSASDAGRIGRLVLPKACAEAFfpliD--QSEGIPIKIQDIMGDEWTFQFRFwpNNNSRMYVLE-GVNACIQNMQVQ 386
                                   99***********************9**543..557788***************9989999999***9.************ PP

                                   TT-E CS
                            B3  76 egDf 79 
                                   +gD+
  Ote100261350041|100261350041 387 AGDT 390
                                   ***7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.107.2E-21306390IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019364.58E-15306390IPR015300DNA-binding pseudobarrel domain
CDDcd100176.35E-18307402No hitNo description
SMARTSM010195.8E-12309403IPR003340B3 DNA binding domain
PfamPF023622.0E-10309390IPR003340B3 DNA binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 663 aa     Download sequence    Send to blast
MGSTNCMNEL CRGTTSSEWK KGWSLKRGGF AVLCCRCGSA YENSVFCETF HSEESGWREC  60
RICRKRIHCG CIASRNLHED MDLGGVGCIT CLKNSEIHSV LSLQVPADVS NGTFSKNGIK  120
DVHPVVVENR IDDDRFSTQG LLQSTKATGT TNGSSGLEQQ KRENPLLKTR QSGTQQSSPS  180
TFYKADNNRP REGAKNMFES LAQPSLNLSL TTLSGSSKSI LPFPGGIAGG SKHKVSLREA  240
LHILPKPSKP NSMVGSEKNR ESVSQARAAK PPAEGRGRNQ LLPRYWPRIT DQELQQISGD  300
LKSNIVPLFE KVLSASDAGR IGRLVLPKAC AEAFFPLIDQ SEGIPIKIQD IMGDEWTFQF  360
RFWPNNNSRM YVLEGVNACI QNMQVQAGDT EPGGQLVIGC RKAINDGDAE DSQTPASTSG  420
DSLSGANSDP LLNGGKSDDS LQQSISEKKK AKNIKNKRLL MHNDDAVELR ITWEEAQELL  480
CPSPTAEPTV VVIEDHEFEE FEEPPIFGTR TIFTSGPLGH SCSVPDDISP NDPEPSVPSY  540
EDSKKKKISE QNVAKGEPSG LDALANAAIL GDSITDTVIT TKHPRHRPGC SCIVCIQPRS  600
GQGKHAPACR CNVCSTVRRR FKTLIMRKKR RISVSEKVKE REDVARDDTR SQINESKGQL  660
DLN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6j9a_A6e-612874102131B3 domain-containing transcription repressor VAL1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor of gene expression involved in embryonic pathways, such as LEC1, ABI3, and FUS3. Repressor of the sugar-inducible genes involved in the seed maturation program in seedlings. Plays an essential role in regulating the transition from seed maturation to seedling growth. Functionally redundant with VAL2/HSL1. {ECO:0000269|PubMed:15894743, ECO:0000269|PubMed:17158584, ECO:0000269|PubMed:17267611}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012841792.10.0PREDICTED: B3 domain-containing transcription repressor VAL1-like
SwissprotQ8W4L51e-180VAL1_ARATH; B3 domain-containing transcription repressor VAL1
TrEMBLA0A4D9AD630.0A0A4D9AD63_SALSN; Uncharacterized protein
STRINGMigut.D00818.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA14912365
Publications ? help Back to Top
  1. Jia H,McCarty DR,Suzuki M
    Distinct roles of LAFL network genes in promoting the embryonic seedling fate in the absence of VAL repression.
    Plant Physiol., 2013. 163(3): p. 1293-305
    [PMID:24043445]
  2. Schneider A, et al.
    Potential targets of VIVIPAROUS1/ABI3-LIKE1 (VAL1) repression in developing Arabidopsis thaliana embryos.
    Plant J., 2016. 85(2): p. 305-19
    [PMID:26678037]
  3. Chhun T, et al.
    HSI2 Repressor Recruits MED13 and HDA6 to Down-Regulate Seed Maturation Gene Expression Directly During Arabidopsis Early Seedling Growth.
    Plant Cell Physiol., 2016. 57(8): p. 1689-706
    [PMID:27335347]
  4. Qüesta JI,Song J,Geraldo N,An H,Dean C
    Arabidopsis transcriptional repressor VAL1 triggers Polycomb silencing at FLC during vernalization.
    Science, 2016. 353(6298): p. 485-8
    [PMID:27471304]
  5. Yuan W, et al.
    A cis cold memory element and a trans epigenome reader mediate Polycomb silencing of FLC by vernalization in Arabidopsis.
    Nat. Genet., 2016. 48(12): p. 1527-1534
    [PMID:27819666]
  6. Merini W, et al.
    The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development.
    Plant Physiol., 2017. 173(1): p. 627-641
    [PMID:27837089]
  7. Li C,Cui Y
    A DNA element that remembers winter.
    Nat. Genet., 2016. 48(12): p. 1451-1452
    [PMID:27898079]
  8. Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
    HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 600-619
    [PMID:29475938]
  9. Sasnauskas G,Kauneckaite K,Siksnys V
    Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1.
    Nucleic Acids Res., 2018. 46(8): p. 4316-4324
    [PMID:29660015]
  10. Wu B, et al.
    Structural insight into the role of VAL1 B3 domain for targeting to FLC locus in Arabidopsis thaliana.
    Biochem. Biophys. Res. Commun., 2018. 501(2): p. 415-422
    [PMID:29733847]