PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

ERF

Protein Properties

Length: 220aa MW: 25133 Da PI: 5.2001

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Niben101Scf01090g02001.1	genome	BTI	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	56.6	6.3e-18	88	138	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr ++ +g+++AeIrd + ng r+++g+f++ae Aa a+++a+ +++g Niben101Scf01090g02001.1 88 NYRGVRKRP-WGKFAAEIRDSTRNG--VRVWIGTFDSAEAAALAYDQAAFAMRG 138 59*****.******44465..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	3.50E-20	87	147	No hit	No description
SuperFamily	SSF54171	7.19E-22	88	148	IPR016177	DNA-binding domain
Pfam	PF00847	3.3E-13	88	138	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.655	88	146	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.2E-29	88	147	IPR001471	AP2/ERF domain
SMART	SM00380	6.6E-36	88	152	IPR001471	AP2/ERF domain
PRINTS	PR00367	7.3E-10	89	100	IPR001471	AP2/ERF domain
PRINTS	PR00367	7.3E-10	112	128	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 220 aa Download sequence Send to blast
MDSSFMHYQN PYDQNYSPHS SSWDEPLFHH NYLPFNVNDT EDMFLFNLVA EGDRTVVKES 60 SAETINTSSS SGTKEEEVTS CEPQKEKNYR GVRKRPWGKF AAEIRDSTRN GVRVWIGTFD 120 SAEAAALAYD QAAFAMRGSL AILNFPVEIV KESLSEMKCR FDEGCSPVIE LKKRHSMRKK 180 TQSRRNIVVR KDESNVVVFE DLGAEHLEEL LSSSECVTNW

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	3e-29	87	149	1	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A	3e-29	85	149	2	66	ATERF1
3gcc_A	3e-29	85	149	2	66	ATERF1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009775978.1	1e-147	PREDICTED: ethylene-responsive transcription factor 1B
Refseq	XP_016511764.1	1e-147	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	5e-98	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A1S4DEV7	1e-146	A0A1S4DEV7_TOBAC; ethylene-responsive transcription factor 1B-like
TrEMBL	A0A1U7WBG5	1e-146	A0A1U7WBG5_NICSY; ethylene-responsive transcription factor 1B
STRING	XP_009775978.1	1e-147	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	2e-49	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]