PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_33675_f_1

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

bZIP

Protein Properties

Length: 321aa MW: 33781.1 Da PI: 5.2678

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_33675_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	75.5	7.3e-24	222	284	1	63
XXXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 1 ekelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 e+elkr++rkq+NRe+ArrsR+RK+ae+eeL+ kv++L++eN+ L++el++l++e++kl se+ Neem_33675_f_1 222 ERELKRQKRKQSNRESARRSRLRKQAECEELQAKVESLTNENRNLRDELQRLSEECEKLSSEN 284 89**********************************************************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF07777	9.1E-23	1	60	IPR012900	G-box binding protein, multifunctional mosaic region
Pfam	PF16596	3.5E-8	89	191	No hit	No description
Gene3D	G3DSA:1.20.5.170	9.4E-21	216	282	No hit	No description
Pfam	PF00170	6.3E-21	222	284	IPR004827	Basic-leucine zipper domain
SMART	SM00338	1.8E-21	222	286	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	13.587	224	287	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	6.33E-12	225	281	No hit	No description
CDD	cd14702	2.15E-24	227	277	No hit	No description
PROSITE pattern	PS00036	0	229	244	IPR004827	Basic-leucine zipper domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 321 aa Download sequence Send to blast
MQAFYGAGAT PPPFFASTVA SPTPHPYLWG SQHPLMPPYG TPVPYPAIYP PGGVYAHPSI 60 ATTPTTAPTN TDLEGKSTEG KDKASAKKSK ATSGGKAGEI GKATSGSGND GVSQSAESGS 120 EGSSDASDEN ANQQDFTGSK KGSFDQMLAD ANAQNNTAEA VPASVPGKPV VSMPATNLNI 180 GMDLWNASSA AAGAAKMRPN PSGAPSAVVP PGMMPEQWIQ DERELKRQKR KQSNRESARR 240 SRLRKQAECE ELQAKVESLT NENRNLRDEL QRLSEECEKL SSENSSIKEE LSRICGAEAV 300 ANLEQSNATS ALQSRADEGN S

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	238	244	RRSRLRK
2	238	245	RRSRLRKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Binds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter (PubMed:1373374). G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control. Binds to the G-box motif 5'-CACGTG-3' of LHCB2.4 (At3g27690) promoter. May act as transcriptional activator in light-regulated expression of LHCB2.4. Probably binds DNA as monomer. DNA-binding activity is redox-dependent (PubMed:22718771). {ECO:0000269\|PubMed:1373374, ECO:0000269\|PubMed:22718771}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006425722.1	0.0	G-box-binding factor 1 isoform X1
Refseq	XP_006425724.1	0.0	G-box-binding factor 1 isoform X1
Refseq	XP_006425726.1	0.0	G-box-binding factor 1 isoform X1
Refseq	XP_006466752.1	0.0	G-box-binding factor 1 isoform X1
Refseq	XP_006466753.1	0.0	G-box-binding factor 1 isoform X1
Refseq	XP_006466754.1	0.0	G-box-binding factor 1 isoform X1
Swissprot	P42774	1e-115	GBF1_ARATH; G-box-binding factor 1
TrEMBL	V4SPD2	0.0	V4SPD2_9ROSI; Uncharacterized protein
STRING	XP_006466752.1	0.0	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7274	26	43

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36730.1	1e-102	G-box binding factor 1

Publications ? help Back to Top
Gangappa SN,Srivastava AK,Maurya JP,Ram H,Chattopadhyay S Z-box binding transcription factors (ZBFs): a new class of transcription factors in Arabidopsis seedling development. Mol Plant, 2013. 6(6): p. 1758-68 [PMID:24157607] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Karumuri S,Bandopadhyay R In silico analysis of the structure and interaction of COP1 protein of Arabidopsis thaliana. Indian J. Biochem. Biophys., 2014. 51(5): p. 343-9 [PMID:25630103] Smykowski A,Zimmermann P,Zentgraf U CORRECTION. G-Box Binding Factor1 Reduces CATALASE2 Expression and Regulates the Onset of Leaf Senescence in Arabidopsis. Plant Physiol., 2016. 170(2): p. 1164-7 [PMID:26826725] Smykowski A,Fischer SM,Zentgraf U Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1. Plants (Basel), 2015. 4(3): p. 691-709 [PMID:27135347] Giri MK, et al. GBF1 differentially regulates CAT2 and PAD4 transcription to promote pathogen defense in Arabidopsis thaliana. Plant J., 2017. 91(5): p. 802-815 [PMID:28622438]