PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Neem_28893_f_1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
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Family | bHLH | ||||||||
Protein Properties | Length: 416aa MW: 47378.7 Da PI: 5.6505 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 38 | 2.9e-12 | 217 | 268 | 1 | 55 |
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +r++h ++Er+RR+++N+ + Lr+l+P + + ++ + a+i A+e++++L+ Neem_28893_f_1 217 QRMTHIAVERNRRKQMNEHLRVLRSLMPGS---YVQRGDQASIIGGAIEFVRELE 268 79****************************...9*****************9995 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:4.10.280.10 | 1.5E-13 | 215 | 271 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd00083 | 4.54E-12 | 215 | 272 | No hit | No description |
SuperFamily | SSF47459 | 2.22E-16 | 216 | 281 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
PROSITE profile | PS50888 | 15.428 | 216 | 267 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 1.3E-9 | 217 | 268 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 3.4E-9 | 222 | 273 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 416 aa Download sequence Send to blast |
MEKEENYSAS FPGLDYSLDH HQHHQDMIVR QRIGETSSDN NHGMIDYMIN NPHQPHQHQQ 60 QISISSSGFC TSNSFDKLSF ADVMQFADFG PKLSLNQTNK LPEEETGIID PVYFLKFPVL 120 NDKLEEDQSL MVSSQPGASN EDQSYKGVEN KERILMEGEM SREDEEIRVS DNINSVQLRF 180 LGGDQDVQNK NNNIVPEGKN KRKRPRAIKT TEEVESQRMT HIAVERNRRK QMNEHLRVLR 240 SLMPGSYVQR GDQASIIGGA IEFVRELEQL LQCLESQKRR RLLGEAAAGV APGGRPIGDP 300 AMAIQPPQQP QLFPPPLPFP NDQMKLMDFE TSLREEMAEN KSCLADVEVK LLGFDAMIKI 360 LSRRRPGQLI KTIAALEDLQ FNILHTNITT IEQTVLYSFN VKVLTFLFII NLKNFS |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 217 | 228 | RMTHIAVERNRR |
2 | 277 | 281 | KRRRL |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269|PubMed:17088607, ECO:0000269|PubMed:17183265, ECO:0000269|PubMed:17183267, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269|PubMed:22442411}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_011045659.1 | 0.0 | PREDICTED: transcription factor FAMA isoform X2 | ||||
Swissprot | Q56YJ8 | 1e-132 | FAMA_ARATH; Transcription factor FAMA | ||||
TrEMBL | B9GFX7 | 0.0 | B9GFX7_POPTR; Uncharacterized protein | ||||
STRING | POPTR_0001s32160.1 | 0.0 | (Populus trichocarpa) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM5548 | 26 | 49 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G24140.1 | 1e-118 | bHLH family protein |