PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe

Family

WRKY

Protein Properties

Length: 583aa MW: 63647.1 Da PI: 6.7854

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Migut.I00135.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	96.3	2.1e-30	262	321	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+aed +++++tYeg+Hnh+ Migut.I00135.1.p 262 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCAEDMSILITTYEGTHNHP 321 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.1E-31	247	323	IPR003657	WRKY domain
SuperFamily	SSF118290	1.83E-27	254	323	IPR003657	WRKY domain
PROSITE profile	PS50811	28.461	257	323	IPR003657	WRKY domain
SMART	SM00774	1.4E-36	262	322	IPR003657	WRKY domain
Pfam	PF03106	7.0E-27	263	321	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 583 aa Download sequence Send to blast
METSLQKSDN EGAVKEEKKA SHDSNGDEES CGDDIFLQIG TGKRAQDDDG MKPSSPNQMN 60 LNSCKELDHQ LGSTKAEMEE VMEENQRLKM YLDQILKDYR TLQMQYRDVI QHESKQEHEQ 120 EQEPTDDLIS LTLGRTTSGT ITERTKPERL KTPTFNNNSN FGGGGVESQR LTLGLDSRFN 180 QVPPNKSSPP PPPETASPPA NPSPENSLEE IRQEAGDAWP PKNTKHARSD NISGGDHEEI 240 SQQNPTKRAR VSVRVRCDTP TMNDGCQWRK YGQKIAKGNP CPRAYYRCTV APSCPVRKQV 300 QRCAEDMSIL ITTYEGTHNH PLPMSATAMA STTSAAASML LSGSSTSGTA ATTSTTSSST 360 TLNGLNFYLS SDNSRSKPYY LPNPHWKSNP LPLSWNNGML SYGTSQPLIN KNHQNTPNNN 420 SLSFGQQQQQ QQQQQQHQQP YETLYQSYMQ KNIPNPSQQT LLPQDTLAAA TKAITSDPSF 480 QSALAAALTS IIGSGGPNNN ISTSLANQNL GAKSAQISDQ PFPILSSFPS TSNANKCAPP 540 HLMNKSSSST SAQTRDLMLL SPPFSNSKSK SNSPGDSSKD QV*

Sequence ? help Back to Top

Protein Sequence Length: 583 aa Download sequence Send to blast

METSLQKSDN EGAVKEEKKA SHDSNGDEES CGDDIFLQIG TGKRAQDDDG MKPSSPNQMN  60
LNSCKELDHQ LGSTKAEMEE VMEENQRLKM YLDQILKDYR TLQMQYRDVI QHESKQEHEQ  120
EQEPTDDLIS LTLGRTTSGT ITERTKPERL KTPTFNNNSN FGGGGVESQR LTLGLDSRFN  180
QVPPNKSSPP PPPETASPPA NPSPENSLEE IRQEAGDAWP PKNTKHARSD NISGGDHEEI  240
SQQNPTKRAR VSVRVRCDTP TMNDGCQWRK YGQKIAKGNP CPRAYYRCTV APSCPVRKQV  300
QRCAEDMSIL ITTYEGTHNH PLPMSATAMA STTSAAASML LSGSSTSGTA ATTSTTSSST  360
TLNGLNFYLS SDNSRSKPYY LPNPHWKSNP LPLSWNNGML SYGTSQPLIN KNHQNTPNNN  420
SLSFGQQQQQ QQQQQQHQQP YETLYQSYMQ KNIPNPSQQT LLPQDTLAAA TKAITSDPSF  480
QSALAAALTS IIGSGGPNNN ISTSLANQNL GAKSAQISDQ PFPILSSFPS TSNANKCAPP  540
HLMNKSSSST SAQTRDLMLL SPPFSNSKSK SNSPGDSSKD QV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	8e-20	249	323	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Migut.I00135.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012839281.1	0.0	PREDICTED: probable WRKY transcription factor 61
Swissprot	A0A3Q7GFB5	1e-131	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A022R6K8	0.0	A0A022R6K8_ERYGU; Uncharacterized protein (Fragment)
STRING	Migut.I00135.1.p	0.0	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	1e-52	WRKY DNA-binding protein 72

Link Out ? help Back to Top
Phytozome	Migut.I00135.1.p

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]