PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr4g065017.1
Common NameMTR_4g065017
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family MYB
Protein Properties Length: 333aa    MW: 37524.4 Da    PI: 5.2177
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr4g065017.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding45.41.8e-141966148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g W++eEde+l ++    G g+W+ +ar  g+ R++k+c++rw +yl
  Medtr4g065017.1 19 KGLWSPEEDEKLMNYMLNSGQGCWSDVARNAGLQRCGKSCRLRWINYL 66
                     678*******************************************97 PP
2Myb_DNA-binding50.26.1e-1672115146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      rg+++++E+e +++++ +lG++ W+ Ia++++ gRt++++k++w++
  Medtr4g065017.1  72 RGAFSPQEEEHIIHLHSLLGNR-WSQIAARLP-GRTDNEIKNFWNS 115
                      89********************.*********.***********97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.602.5E-231369IPR009057Homeodomain-like
PROSITE profilePS5129415.561466IPR017930Myb domain
SuperFamilySSF466891.29E-2717113IPR009057Homeodomain-like
SMARTSM007179.9E-101868IPR001005SANT/Myb domain
PfamPF002496.9E-131966IPR001005SANT/Myb domain
CDDcd001671.85E-82266No hitNo description
PROSITE profilePS5129424.67467121IPR017930Myb domain
Gene3DG3DSA:1.10.10.608.4E-2670122IPR009057Homeodomain-like
SMARTSM007173.0E-1471119IPR001005SANT/Myb domain
PfamPF002491.1E-1472115IPR001005SANT/Myb domain
CDDcd001674.45E-1074114No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000652Biological Processregulation of secondary cell wall biogenesis
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 333 aa     Download sequence    Send to blast
MRKPDIASGK NNTNNKLRKG LWSPEEDEKL MNYMLNSGQG CWSDVARNAG LQRCGKSCRL  60
RWINYLRPDL KRGAFSPQEE EHIIHLHSLL GNRWSQIAAR LPGRTDNEIK NFWNSTIKKR  120
LKNMSLNTSP NASDESSYDP NKDHNMGGFI TSSTQDQQHI DNHFMPMFNT SSPSPPTMQN  180
TVFNTIMSGS GCGFFNNSTT GTYLSQNNHD SKSFYLEKVF GSVNIINGVE GDEMEIYNVP  240
PLESVNSTIT SEHSVKMENA CNGEDGNYNS SYNFDDINNI VINNCNVVSK RSENRVDDEV  300
ENLFHGDLSV GDWNLEDLMK DVSSFPFLDF SN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A2e-26171215108B-MYB
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed specifically in fiber and vessel cells that are undergoing secondary wall thickening in floral stems. Expressed in vessels but not in xylary fibers in the developing secondary xylem of roots. {ECO:0000269|PubMed:19808805}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that acts as molecular switch in the NAC012/SND1-mediated transcriptional network regulating secondary wall biosynthesis. Is directly activated by NAC012/SND1 and its close homologs, including NAC043/NST1, NAC066/NST2, NAC101/VND6 and NAC030/VND7. Is required for functional expression of a number of secondary wall-associated transcription factors and secondary wall biosynthetic genes involved in cellulose, xylan and lignin synthesis. Functions redundantly with MYB46 in the transcriptional regulatory cascade leading to secondary wall formation in fibers and vessels (PubMed:19808805). Transcription activator that binds to the DNA consensus sequence 5'-ACC[AT]A[AC][TC]-3', designated as the secondary wall MYB-responsive element (SMRE). Regulates directly numerous transcription factors and a number of genes involved in secondary wall biosynthesis that contain SMRE elements in their promoters (PubMed:22197883). {ECO:0000269|PubMed:19808805, ECO:0000269|PubMed:22197883}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00336DAPTransfer from AT3G08500Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr4g065017.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT1400969e-96BT140096.1 Lotus japonicus clone JCVI-FLLj-12H15 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013456181.10.0transcription factor MYB46
SwissprotQ9C6U17e-75MYB83_ARATH; Transcription factor MYB83
TrEMBLA0A072UKG90.0A0A072UKG9_MEDTR; Myb transcription factor
STRINGXP_004507092.11e-172(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF77434128
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G08500.13e-76myb domain protein 83
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Vargas L, et al.
    Improving total saccharification yield of Arabidopsis plants by vessel-specific complementation of caffeoyl shikimate esterase (cse) mutants.
    Biotechnol Biofuels, 2016. 9: p. 139
    [PMID:27390589]
  3. Piya S,Kihm C,Rice JH,Baum TJ,Hewezi T
    Cooperative Regulatory Functions of miR858 and MYB83 during Cyst Nematode Parasitism.
    Plant Physiol., 2017. 174(3): p. 1897-1912
    [PMID:28512179]