PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Manes.17G023100.1.p

Organism

Manihot esculenta

Taxonomic ID

3983

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

WRKY

Protein Properties

Length: 529aa MW: 57115.1 Da PI: 5.9767

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.17G023100.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	96.1	2.3e-30	199	258	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a Cpv+k+v+r+aed +++++tYeg+Hnh+ Manes.17G023100.1.p 199 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApACPVRKQVQRCAEDMSILITTYEGTHNHP 258 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.4E-31	184	260	IPR003657	WRKY domain
SuperFamily	SSF118290	3.27E-27	192	260	IPR003657	WRKY domain
PROSITE profile	PS50811	28.461	194	260	IPR003657	WRKY domain
SMART	SM00774	2.2E-36	199	259	IPR003657	WRKY domain
Pfam	PF03106	7.7E-27	200	258	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006952	Biological Process	defense response
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 529 aa Download sequence Send to blast
MDNSAALPPL ITHKDGSIQD SDIKEDVLES AKAEMGEVRE ENERLKMMLQ QVEKDYQSLK 60 LRFFDILRQE TCKKPADSAP SSDETEEPEL VSLCLGRTPS EPKRDEKTSN SSKSSRENEE 120 LKASLTLGFE SKFQTSTELV SNPSPENSLE DLAKEDEAAG ETWPPSKVLK RNADDEVAQQ 180 NNVKRARVCV RARCDTPTMN DGCQWRKYGQ KIAKGNPCPR AYYRCTVAPA CPVRKQVQRC 240 AEDMSILITT YEGTHNHPLP VSATAMASTT SAAASMLLSG SSSSQPAFGS HAAATTTTAT 300 QLNGLSFSLY DSSTPKQFYL ANNSSSPLFP TITLDLTASP STSSTATPFN NRFSSSISRF 360 PSTNLNFCSS ESNIVSEVWG NGYQTRKQLQ EQIYEKNHQN QAASQQELTE TLTKAITSDP 420 SFRTVIAAAI SSMMGGGGGS ANSSQGNLRG AESFGQNLKL GEGNNQAIAA NLLNLQNGKG 480 CASSYFNGLS ASTSQMGSLL QSHALPFSVF NSSSMSANNN NNNKDHKS*

Sequence ? help Back to Top

Protein Sequence Length: 529 aa Download sequence Send to blast

MDNSAALPPL ITHKDGSIQD SDIKEDVLES AKAEMGEVRE ENERLKMMLQ QVEKDYQSLK  60
LRFFDILRQE TCKKPADSAP SSDETEEPEL VSLCLGRTPS EPKRDEKTSN SSKSSRENEE  120
LKASLTLGFE SKFQTSTELV SNPSPENSLE DLAKEDEAAG ETWPPSKVLK RNADDEVAQQ  180
NNVKRARVCV RARCDTPTMN DGCQWRKYGQ KIAKGNPCPR AYYRCTVAPA CPVRKQVQRC  240
AEDMSILITT YEGTHNHPLP VSATAMASTT SAAASMLLSG SSSSQPAFGS HAAATTTTAT  300
QLNGLSFSLY DSSTPKQFYL ANNSSSPLFP TITLDLTASP STSSTATPFN NRFSSSISRF  360
PSTNLNFCSS ESNIVSEVWG NGYQTRKQLQ EQIYEKNHQN QAASQQELTE TLTKAITSDP  420
SFRTVIAAAI SSMMGGGGGS ANSSQGNLRG AESFGQNLKL GEGNNQAIAA NLLNLQNGKG  480
CASSYFNGLS ASTSQMGSLL QSHALPFSVF NSSSMSANNN NNNKDHKS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	4e-22	186	260	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.17G023100.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KT827582	0.0	KT827582.1 Manihot esculenta WRKY transcription factor 7 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021599875.1	0.0	probable WRKY transcription factor 72
Swissprot	A0A3Q7GFB5	1e-119	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A140H8L1	0.0	A0A140H8L1_MANES; WRKY transcription factor 7
STRING	cassava4.1_026182m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF650	34	134

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	4e-74	WRKY DNA-binding protein 72

Link Out ? help Back to Top
Phytozome	Manes.17G023100.1.p

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371] Wei Y, et al. Genome-Wide Identification and Expression Analysis of the WRKY Gene Family in Cassava. Front Plant Sci, 2016. 7: p. 25 [PMID:26904033]