PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Manes.15G179400.1.p

Organism

Manihot esculenta

Taxonomic ID

3983

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

WRKY

Protein Properties

Length: 465aa MW: 49851.1 Da PI: 6.2596

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.15G179400.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	93.8	1.3e-29	146	204	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 +Dg++WrKYGqK kg+++pr+YYrCt +Cpv+k+v+r+aed +++++tYeg Hnh+ Manes.15G179400.1.p 146 NDGCQWRKYGQKIAKGNPCPRAYYRCTVIpKCPVRKQVQRCAEDMSILITTYEGIHNHP 204 8************************988**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	2.6E-31	130	206	IPR003657	WRKY domain
SuperFamily	SSF118290	3.14E-27	138	206	IPR003657	WRKY domain
PROSITE profile	PS50811	27.646	140	206	IPR003657	WRKY domain
SMART	SM00774	2.9E-35	145	205	IPR003657	WRKY domain
Pfam	PF03106	7.1E-26	146	204	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 465 aa Download sequence Send to blast
MEKDYQSLKF HFFDLLGQET CKKSEDSTPS SDETEESELV SLCLGRTPSE SKKYEKGSNS 60 SRSSRENEDL EAGLTLGLDS KFQMSTELES NPSPENSLDA KEDEAGETWP PSKILKRNID 120 DEDAKQGDVK RARVCVRARC ETPTINDGCQ WRKYGQKIAK GNPCPRAYYR CTVIPKCPVR 180 KQVQRCAEDM SILITTYEGI HNHPLPVSAT AMASTTSAAA SMLLSGSSAS QPTLIGSHAS 240 ATQLNGLSFN NLYDSSTTKQ FYIANNPSSP LCPTITLDLT ASPSTASSAT PPFNWFSSSF 300 TSPSRFPSTS LNFPSPAVWS NGYQNSYGSS LSNLGPYMEK NHQQQALTET LTKAIISDPS 360 FRTVIAAAIS SMVAGNGSAS ASSSQGNQRA AENFGQNLRL GEANNEAVST SSLNLQNGKG 420 CAPSYISGLS SSSQIGLLQS HVLPSCVLNS ASLAANNNNK DQKN*

Sequence ? help Back to Top

Protein Sequence Length: 465 aa Download sequence Send to blast

MEKDYQSLKF HFFDLLGQET CKKSEDSTPS SDETEESELV SLCLGRTPSE SKKYEKGSNS  60
SRSSRENEDL EAGLTLGLDS KFQMSTELES NPSPENSLDA KEDEAGETWP PSKILKRNID  120
DEDAKQGDVK RARVCVRARC ETPTINDGCQ WRKYGQKIAK GNPCPRAYYR CTVIPKCPVR  180
KQVQRCAEDM SILITTYEGI HNHPLPVSAT AMASTTSAAA SMLLSGSSAS QPTLIGSHAS  240
ATQLNGLSFN NLYDSSTTKQ FYIANNPSSP LCPTITLDLT ASPSTASSAT PPFNWFSSSF  300
TSPSRFPSTS LNFPSPAVWS NGYQNSYGSS LSNLGPYMEK NHQQQALTET LTKAIISDPS  360
FRTVIAAAIS SMVAGNGSAS ASSSQGNQRA AENFGQNLRL GEANNEAVST SSLNLQNGKG  420
CAPSYISGLS SSSQIGLLQS HVLPSCVLNS ASLAANNNNK DQKN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	5e-21	132	206	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.15G179400.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KT827599	0.0	KT827599.1 Manihot esculenta WRKY transcription factor 24 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021595743.1	0.0	probable WRKY transcription factor 72
Swissprot	A0A3Q7GFB5	9e-94	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A2C9UH06	0.0	A0A2C9UH06_MANES; Uncharacterized protein
STRING	cassava4.1_026182m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF650	34	134

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	4e-61	WRKY DNA-binding protein 72

Link Out ? help Back to Top
Phytozome	Manes.15G179400.1.p

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]