PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

MIKC_MADS

Protein Properties

Length: 217aa MW: 24983.5 Da PI: 9.3186

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C026300P2	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	100.1	8.5e-32	9	59	1	51
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 krienk+nrqvtf+kRrng+lKKA+ELSvLCdaeva+iifs++gklye++s MELO3C026300P2 9 KRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEVALIIFSNRGKLYEFCS 59 79***********************************************96 PP
2	K-box	99.4	5.1e-33	83	173	10	100
K-box 10 eeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkklee 100 +++ es+++e+ kLk++ e+Lqr+qR+llGedL++L+ keL+qLe+qLe+slk++Rs+K++++l+q+++lq+ke++l e+n+aL++klee MELO3C026300P2 83 PAKELESSYREYVKLKSRFESLQRTQRNLLGEDLGPLNSKELEQLERQLESSLKQVRSTKTQYMLDQLSDLQNKEQMLIETNRALQMKLEE 173 5678999*********************************************************************************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50066	32.66	1	61	IPR002100	Transcription factor, MADS-box
SMART	SM00432	6.6E-40	1	60	IPR002100	Transcription factor, MADS-box
SuperFamily	SSF55455	6.67E-33	2	77	IPR002100	Transcription factor, MADS-box
CDD	cd00265	7.57E-43	2	76	No hit	No description
PRINTS	PR00404	8.3E-32	3	23	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	1.8E-26	10	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	8.3E-32	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	8.3E-32	38	59	IPR002100	Transcription factor, MADS-box
Pfam	PF01486	7.0E-27	84	171	IPR002487	Transcription factor, K-box
PROSITE profile	PS51297	15.59	87	177	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009611	Biological Process	response to wounding
GO:0048481	Biological Process	plant ovule development
GO:0071486	Biological Process	cellular response to high light intensity
GO:0071492	Biological Process	cellular response to UV-A
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 217 aa Download sequence Send to blast
MGRGIVELKR IENKINRQVT FAKRRNGLLK KAYELSVLCD AEVALIIFSN RGKLYEFCST 60 SNMLKTLERY QKCSYGAVEV TKPAKELESS YREYVKLKSR FESLQRTQRN LLGEDLGPLN 120 SKELEQLERQ LESSLKQVRS TKTQYMLDQL SDLQNKEQML IETNRALQMK LEEISSRNNI 180 RHPWDGGDQS MSYGTQNAQT QGFFQPLDCN PTLQIG*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ox0_A	3e-36	75	171	1	101	Developmental protein SEPALLATA 3
4ox0_B	3e-36	75	171	1	101	Developmental protein SEPALLATA 3
4ox0_C	3e-36	75	171	1	101	Developmental protein SEPALLATA 3
4ox0_D	3e-36	75	171	1	101	Developmental protein SEPALLATA 3
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in flower development. {ECO:0000250\|UniProtKB:Q0HA25}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF135962	0.0	AF135962.1 Cucumis sativus CAGL2 (CAGL2) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008464576.1	1e-158	PREDICTED: developmental protein SEPALLATA 1
Swissprot	Q8LLR2	1e-132	MADS2_VITVI; Agamous-like MADS-box protein MADS2
TrEMBL	A0A1S3CLU0	1e-157	A0A1S3CLU0_CUCME; developmental protein SEPALLATA 1
STRING	XP_008464576.1	1e-158	(Cucumis melo)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G02310.1	1e-107	MIKC_MADS family protein

Publications ? help Back to Top
Jaillon O, et al. The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla. Nature, 2007. 449(7161): p. 463-7 [PMID:17721507] Díaz-Riquelme J,Lijavetzky D,Martínez-Zapater JM,Carmona MJ Genome-wide analysis of MIKCC-type MADS box genes in grapevine. Plant Physiol., 2009. 149(1): p. 354-69 [PMID:18997115] Grimplet J,Martínez-Zapater JM,Carmona MJ Structural and functional annotation of the MADS-box transcription factor family in grapevine. BMC Genomics, 2016. 17: p. 80 [PMID:26818751]