PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MELO3C023668P1

Organism

Cucumis melo

Taxonomic ID

3656

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

C2H2

Protein Properties

Length: 513aa MW: 56750.6 Da PI: 6.2676

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C023668P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	20.9	9.2e-07	260	281	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C +Cgk F+r nL+ H+r H MELO3C023668P1 260 FCAICGKGFKRDANLRMHMRGH 281 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.29E-5	257	285	No hit	No description
SMART	SM00355	0.012	259	281	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	11.884	259	286	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	1.2E-5	260	310	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	261	281	IPR007087	Zinc finger, C2H2
SMART	SM00355	63	308	341	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	15	346	368	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010044	Biological Process	response to aluminum ion
GO:0010447	Biological Process	response to acidic pH
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 513 aa Download sequence Send to blast
MEPEDSLCSS EVWTKSSSFP NNNVQQPPQK WPDTSILDYA MDQPFQEFQE RTESKASLAC 60 NPNQQIEILD KDSNQMNAAL LASKIQDWDP RAMLNNLSFL EQKIHQLQEL VHLIVGRRSQ 120 VFGRPDELVV QQQQLITADL TSIIVQLIST AGSLLPSVKH NLSAAVPPVG QLEQFNKVIF 180 ASEPGTNGGV QSQHGDGAKL PEFPSQVDGS SKCGKEQNMT VEEHESKDEE DADENENLPP 240 GSYEILQLEK EEILAPHTHF CAICGKGFKR DANLRMHMRG HGDEYKTAAA LAKPNKELGS 300 ETMLIKRYSC PFTGCKRNKE HKKFQPLKTI LCVKNHYKRT HCDKSFTCSK CNSKKFSVIA 360 DLKTHEKHCG KDKWLCSCGT TFSRKDKLFG HIALFQGHTP AIPLDESKGA AMSCDRGERY 420 ETTNKLGSIN FSFGSIASGG SSVETIADAK GGVDDPLSYF SPLNFDSCNF GGFHEFPRPP 480 FENTDNAFSF LIPGSGNYTQ KSGAESSSNN LE*

Sequence ? help Back to Top

Protein Sequence Length: 513 aa Download sequence Send to blast

MEPEDSLCSS EVWTKSSSFP NNNVQQPPQK WPDTSILDYA MDQPFQEFQE RTESKASLAC  60
NPNQQIEILD KDSNQMNAAL LASKIQDWDP RAMLNNLSFL EQKIHQLQEL VHLIVGRRSQ  120
VFGRPDELVV QQQQLITADL TSIIVQLIST AGSLLPSVKH NLSAAVPPVG QLEQFNKVIF  180
ASEPGTNGGV QSQHGDGAKL PEFPSQVDGS SKCGKEQNMT VEEHESKDEE DADENENLPP  240
GSYEILQLEK EEILAPHTHF CAICGKGFKR DANLRMHMRG HGDEYKTAAA LAKPNKELGS  300
ETMLIKRYSC PFTGCKRNKE HKKFQPLKTI LCVKNHYKRT HCDKSFTCSK CNSKKFSVIA  360
DLKTHEKHCG KDKWLCSCGT TFSRKDKLFG HIALFQGHTP AIPLDESKGA AMSCDRGERY  420
ETTNKLGSIN FSFGSIASGG SSVETIADAK GGVDDPLSYF SPLNFDSCNF GGFHEFPRPP  480
FENTDNAFSF LIPGSGNYTQ KSGAESSSNN LE*

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00196	ampDAP	Transfer from AT1G34370	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681794	0.0	LN681794.1 Cucumis melo genomic scaffold, anchoredscaffold00061.
GenBank	LN713255	0.0	LN713255.1 Cucumis melo genomic chromosome, chr_1.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008461471.1	0.0	PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1
Swissprot	Q9C8N5	0.0	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	A0A1S3CEP8	0.0	A0A1S3CEP8_CUCME; protein SENSITIVE TO PROTON RHIZOTOXICITY 1
STRING	XP_008461471.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5340	32	54

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	0.0	C2H2 family protein

Publications ? help Back to Top
Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]