PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

Dof

Protein Properties

Length: 341aa MW: 36145.1 Da PI: 9.8407

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C009265P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	123.8	5.8e-39	78	137	3	62
zf-Dof 3 ekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 e+alkcprC+stntkfCy+nnysl+qPr+fCk+CrryWt+GGalrnvPvGgg+r+nk+++ MELO3C009265P1 78 EAALKCPRCESTNTKFCYFNNYSLTQPRHFCKTCRRYWTRGGALRNVPVGGGCRRNKRTK 137 7789*****************************************************975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101447	3.92E-5	41	48	No hit	No description
ProDom	PD007478	1.0E-36	61	135	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	1.5E-32	80	135	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	29.544	81	135	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	83	119	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 341 aa Download sequence Send to blast
MNFSSIPPYL DPSNWQQQVT HQVGTSSSTA VSSQLLPPPP PPPPPPPPPP PHGIGGAGSI 60 RPGSMAERAR MANIPMPEAA LKCPRCESTN TKFCYFNNYS LTQPRHFCKT CRRYWTRGGA 120 LRNVPVGGGC RRNKRTKGSS SKSPPVSSDR QQTSGSANSS SSAIASNNSG GLSPQIPPLG 180 RFMAPLHQQL SDFDIGSYSY GGGLSAPATA TGDLNFHLGN TNLGGGTSIG SLLGFDQQQW 240 RLQQQPPQFP FLSSLDPFEG GNGGGGEAPG TGWPMRPKVP SRNNLTQMGN SVKMEETPDQ 300 VNNNVGRQLI GNNEQYWSSG SMAWSDLSGF SSSSSTRNPL *

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Probably involved in early processes for vascular development (PubMed:17583520). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements. Triggers the transcription of HD-ZIP III genes, especially in the central domain of vascular tissue (PubMed:30626969). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:17583520, ECO:0000269\|PubMed:30626969}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00295	DAP	Transfer from AT2G37590	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cytokinin in procambium. Antagonized by the HD-ZIP III proteins and by mobile miR165 and miR166 microRNAs. {ECO:0000269\|PubMed:30626969}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681841	0.0	LN681841.1 Cucumis melo genomic scaffold, anchoredscaffold00011.
GenBank	LN713258	0.0	LN713258.1 Cucumis melo genomic chromosome, chr_4.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008442559.1	0.0	PREDICTED: dof zinc finger protein DOF5.1-like isoform X1
Swissprot	O80928	2e-52	DOF24_ARATH; Dof zinc finger protein DOF2.4
TrEMBL	A0A1S3B5Z3	0.0	A0A1S3B5Z3_CUCME; dof zinc finger protein DOF5.1-like isoform X1
STRING	XP_008442559.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF656	34	143

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G37590.1	3e-50	DNA binding with one finger 2.4

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]