PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C005281P1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family C2H2
Protein Properties Length: 473aa    MW: 52157.1 Da    PI: 5.9353
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C005281P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.80.00018123145123
                     EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                     ++Cp+Cg+s+++ ++   H  ++
  MELO3C005281P1 123 FECPICGRSYRSEEEVSEHVDSC 145
                     89************999998766 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.10.20.905.3E-102452No hitNo description
SMARTSM007343.9E-4122146IPR006642Zinc finger, Rad18-type putative
PROSITE profilePS501579.162123154IPR007087Zinc finger, C2H2
CDDcd092122.00E-19170243No hitNo description
SuperFamilySSF1435033.66E-17182258IPR018997PUB domain
PfamPF094092.4E-16183254IPR018997PUB domain
SMARTSM005801.9E-16183250IPR018997PUB domain
SuperFamilySSF542364.91E-15324436IPR029071Ubiquitin-related domain
Gene3DG3DSA:3.10.20.905.3E-10340434No hitNo description
SMARTSM001660.0011349438IPR001012UBX domain
PROSITE profilePS5003312.794352436IPR001012UBX domain
PfamPF007898.8E-7353434IPR001012UBX domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006281Biological ProcessDNA repair
GO:0050832Biological Processdefense response to fungus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 473 aa     Download sequence    Send to blast
MGDVKDKVKG FMKRFNNTLS SSSSTSFKGQ GRVLGSSSSG STSSLPTRPS ENPISKPKLV  60
SPPSNFSANS NPPVANSIAT GQNRSDPSNK SNPDRKRADG FDPFDSFITS GKRSGNGYSL  120
NVFECPICGR SYRSEEEVSE HVDSCVNVST AKGPEDPPTS DAESRSELEA CIGTFLAGKP  180
SQGSLDIVLK LLRNIVREPE NSKFRKIRLS NPKIKEAIGE AVGGVELLEF VGFKLQEEDG  240
EMWATMEVPT EEQIHLLNKV IDSIDRPKLE EQQEKASTAP ELIEPKKVDR QIRVFFAVPE  300
NIAANIELPD SFYTLSVEEV KREAIMRKKK IAESQLLVPK SYKEKQAKAA RRKYTRTVIR  360
IQFPDGVVLQ GVFSPWEPTN TLYEFVSTAL KEPCLEFELI HPVGVKRRTI AHFPAEEDKS  420
KTLDDEELVP SALVKFRPIE TDSVVFTGLR NELLEIIEPL VSGSAVAPPT QV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5ifs_A5e-1330343619146Tether containing UBX domain for GLUT4
5ifs_C5e-1330343619146Tether containing UBX domain for GLUT4
5ifw_A2e-1330743623146Tether containing UBX domain for GLUT4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtFacilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269|PubMed:19176722, ECO:0000269|PubMed:23301616, ECO:0000269|Ref.8}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269|PubMed:19176722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818950.0LN681895.1 Cucumis melo genomic scaffold, anchoredscaffold00005.
GenBankLN7132630.0LN713263.1 Cucumis melo genomic chromosome, chr_9.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008467106.10.0PREDICTED: plant UBX domain-containing protein 2
SwissprotQ9ZU931e-179PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBLA0A1S3CSR10.0A0A1S3CSR1_CUCME; plant UBX domain-containing protein 2
STRINGXP_008467106.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF89442529
Publications ? help Back to Top
  1. Suzuki T,Park H,Till EA,Lennarz WJ
    The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway.
    Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7
    [PMID:11587532]
  2. Rancour DM,Park S,Knight SD,Bednarek SY
    Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48.
    J. Biol. Chem., 2004. 279(52): p. 54264-74
    [PMID:15498773]
  3. Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC
    Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction.
    Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45
    [PMID:23301616]