PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000539118

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

NF-YC

Protein Properties

Length: 252aa MW: 28006.5 Da PI: 6.3681

Description

NF-YC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000539118	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NF-YC	176.2	3.1e-55	70	173	1	101
NF-YC 1 qlksfwekq...iekatdfknhelPlarikkilkadedvkmisaeaPvllskacelfileltlrswlhaeenkrrtlkksdiaaavtrtdifdflv 93 ql++fw +q i++++dfknh+lPlarikki+kadedv+misaeaPv++++ace+filelt+rsw+h+eenkrrtl+k+diaaa+trtdifdflv MDP0000539118 70 QLQKFWGEQhkeIDQTNDFKNHSLPLARIKKIMKADEDVRMISAEAPVIFARACEMFILELTMRSWNHTEENKRRTLQKNDIAAAITRTDIFDFLV 165 89**9998889******************************************************************************* PP NF-YC 94 divprdel 101 divpr++l MDP0000539118 166 DIVPREDL 173 ***987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47113	5.2E-34	44	164	IPR009072	Histone-fold
Gene3D	G3DSA:1.10.20.10	5.4E-38	84	156	IPR009072	Histone-fold
Pfam	PF00808	2.0E-21	92	155	IPR003958	Transcription factor CBF/NF-Y/archaeal histone domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0005829	Cellular Component	cytosol
GO:0046982	Molecular Function	protein heterodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 252 aa Download sequence Send to blast
MDQQGHGHPA TMGVAGTAAQ ASYGVNPYGS VGMMQSPTQP AGSAASSQLA QHQLAYQHIH 60 QQQQQQLQQQ LQKFWGEQHK EIDQTNDFKN HSLPLARIKK IMKADEDVRM ISAEAPVIFA 120 RACEMFILEL TMRSWNHTEE NKRRTLQKND IAAAITRTDI FDFLVDIVPR EDLKDEVLAS 180 IPRGGNPPVG GPSDGVPYYY MPPQHASQVG APAMIVGKPV MDQNLYGQQA HPYIAQPTWP 240 QQQQHPHDDL E*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5g49_B	1e-60	78	170	3	95	NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT C-3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	142	148	RRTLQKN

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.13270	0.0	bud\| fruit\| root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitous. Present in etiolated seedlings. {ECO:0000269\|PubMed:11867211, ECO:0000269\|PubMed:17322342}.

Functional Description ? help Back to Top
Source	Description
UniProt	Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity). Interacts with REF6 to directly regulate SOC1 transcription in response to flowering signals from photoperiod and gibberellic acid pathways (PubMed:25105952). {ECO:0000250, ECO:0000269\|PubMed:25105952}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008390839.1	0.0	nuclear transcription factor Y subunit C-3-like
Swissprot	Q8L4B2	1e-81	NFYC9_ARATH; Nuclear transcription factor Y subunit C-9
TrEMBL	A0A498I9D3	0.0	A0A498I9D3_MALDO; Uncharacterized protein
STRING	XP_008351229.1	0.0	(Malus domestica)
STRING	XP_008390839.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1257	34	108

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G08970.4	4e-78	nuclear factor Y, subunit C9

Link Out ? help Back to Top
Phytozome	MDP0000539118

Publications ? help Back to Top
Hwang YH, et al. Functional conservation of rice OsNF-YB/YC and Arabidopsis AtNF-YB/YC proteins in the regulation of flowering time. Plant Cell Rep., 2016. 35(4): p. 857-65 [PMID:26754793] Liu X, et al. The NF-YC-RGL2 module integrates GA and ABA signalling to regulate seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 12768 [PMID:27624486] Myers ZA, et al. NUCLEAR FACTOR Y, Subunit C (NF-YC) Transcription Factors Are Positive Regulators of Photomorphogenesis in Arabidopsis thaliana. PLoS Genet., 2016. 12(9): p. e1006333 [PMID:27685091] Tang Y, et al. Arabidopsis NF-YCs Mediate the Light-Controlled Hypocotyl Elongation via Modulating Histone Acetylation. Mol Plant, 2017. 10(2): p. 260-273 [PMID:27876642] Zhao H, et al. The Arabidopsis thaliana Nuclear Factor Y Transcription Factors. Front Plant Sci, 2016. 7: p. 2045 [PMID:28119722] Gnesutta N, et al. CONSTANS Imparts DNA Sequence Specificity to the Histone Fold NF-YB/NF-YC Dimer. Plant Cell, 2017. 29(6): p. 1516-1532 [PMID:28526714] Bi C,Ma Y,Wang XF,Zhang DP Overexpression of the transcription factor NF-YC9 confers abscisic acid hypersensitivity in Arabidopsis. Plant Mol. Biol., 2017. 95(4-5): p. 425-439 [PMID:28924726] Liu X, et al. Temporal-Specific Interaction of NF-YC and CURLY LEAF during the Floral Transition Regulates Flowering. Plant Physiol., 2018. 177(1): p. 105-114 [PMID:29599268]