PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000257674

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

NAC

Protein Properties

Length: 395aa MW: 44743.5 Da PI: 7.3635

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000257674	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	172.2	1.6e-53	9	138	1	129
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 +ppGfrFhPtdeel+++yLkkkv+ +k+++ evi+evd++k+ePwdL++ ++ + ++ewyfFs++d+ky+tg+r+nrat++g+Wkatg+dk + MDP0000257674 9 VPPGFRFHPTDEELLHYYLKKKVSFQKFDM-EVIREVDLNKMEPWDLQErcRIGStPQNEWYFFSHKDRKYPTGSRTNRATNAGFWKATGRDKCIR 103 69**************************.99**********963433332556********************************* PP NAM 94 skkgelvglkktLvfykgrapkgektdWvmheyrle 129 + + +++g++ktLvfy+grap+g+ktdW+mheyrle MDP0000257674 104 N-TFKQIGMRKTLVFYRGRAPHGQKTDWIMHEYRLE 138 9.8999**************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.83E-59	7	161	IPR003441	NAC domain
PROSITE profile	PS51005	57.802	9	161	IPR003441	NAC domain
Pfam	PF02365	7.4E-28	10	137	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 395 aa Download sequence Send to blast
MANSSSGGVP PGFRFHPTDE ELLHYYLKKK VSFQKFDMEV IREVDLNKME PWDLQERCRI 60 GSTPQNEWYF FSHKDRKYPT GSRTNRATNA GFWKATGRDK CIRNTFKQIG MRKTLVFYRG 120 RAPHGQKTDW IMHEYRLEDG DDPDGNLSSE DGWVICRVFK KKNLFKVANE GGSSSMNSSD 180 HQQLKNTSSN SQLQARSFMH SHRDNQYLLR QQHHAAAQAF ELNNNPSLHY AHLQPPPPYS 240 LFQSQALIPT LAHKPLSAYD DYSSQHPSDD SPSHGMVKQL MTNPRDRESG SEGLRYQACE 300 PVLEVGTCEP NHQLNTVAGG AGAAGGRDNN HDHQGMSEWA MLDRLVTSHD LGNDQDSSSK 360 GAARYEDANA PSSVNQINPQ HLSLRGEMDF WGYAK

Sequence ? help Back to Top

Protein Sequence Length: 395 aa Download sequence Send to blast

MANSSSGGVP PGFRFHPTDE ELLHYYLKKK VSFQKFDMEV IREVDLNKME PWDLQERCRI  60
GSTPQNEWYF FSHKDRKYPT GSRTNRATNA GFWKATGRDK CIRNTFKQIG MRKTLVFYRG  120
RAPHGQKTDW IMHEYRLEDG DDPDGNLSSE DGWVICRVFK KKNLFKVANE GGSSSMNSSD  180
HQQLKNTSSN SQLQARSFMH SHRDNQYLLR QQHHAAAQAF ELNNNPSLHY AHLQPPPPYS  240
LFQSQALIPT LAHKPLSAYD DYSSQHPSDD SPSHGMVKQL MTNPRDRESG SEGLRYQACE  300
PVLEVGTCEP NHQLNTVAGG AGAAGGRDNN HDHQGMSEWA MLDRLVTSHD LGNDQDSSSK  360
GAARYEDANA PSSVNQINPQ HLSLRGEMDF WGYAK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	2e-51	9	163	17	167	NO APICAL MERISTEM PROTEIN
1ut4_B	2e-51	9	163	17	167	NO APICAL MERISTEM PROTEIN
1ut7_A	2e-51	9	163	17	167	NO APICAL MERISTEM PROTEIN
1ut7_B	2e-51	9	163	17	167	NO APICAL MERISTEM PROTEIN
4dul_A	2e-51	9	163	17	167	NAC domain-containing protein 19
4dul_B	2e-51	9	163	17	167	NAC domain-containing protein 19
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Detectable in lateral root development when they reach 10 mm long. {ECO:0000269\|PubMed:20197506}.
Uniprot	TISSUE SPECIFICITY: Expressed throughout the root cap, in both columella (COL) and lateral root cap (LRC) cells, with higher levels in the COL-adjoining LRC than the upper LRC. Also present at low levels expression in the tips of cotyledons and the cotyledon vasculature, as weel as in vasculature of the first pair of true leaves and at the hydathodes. {ECO:0000269\|PubMed:20197506}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator. Together with BRN1 and SMB, regulates cellular maturation of root cap. Promotes the expression of genes involved in secondary cell walls (SCW) biosynthesis. {ECO:0000269\|PubMed:20197506}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008346421.1	0.0	protein BEARSKIN2-like
Swissprot	Q9SV87	1e-153	BRN2_ARATH; Protein BEARSKIN2
TrEMBL	A0A498K3U6	0.0	A0A498K3U6_MALDO; Uncharacterized protein
STRING	XP_008346421.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8752	33	43

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G10350.1	1e-149	NAC domain containing protein 70

Link Out ? help Back to Top
Phytozome	MDP0000257674

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Kamiya M, et al. Control of root cap maturation and cell detachment by BEARSKIN transcription factors in Arabidopsis. Development, 2016. 143(21): p. 4063-4072 [PMID:27803060]