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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
MDP0000187830 |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
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| Family |
E2F/DP |
| Protein Properties |
Length: 459aa MW: 50562.1 Da PI: 5.3395 |
| Description |
E2F/DP family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| MDP0000187830 | genome | GDR | View CDS |
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| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | E2F_TDP | 77.8 | 9.9e-25 | 157 | 216 | 7 | 71 |
E2F_TDP 7 rlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg
MDP0000187830 157 GLLTKKFINLIKRAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 216
68**************************...99..****************************98 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated |
| GO:0051446 | Biological Process | positive regulation of meiotic cell cycle |
| GO:0005667 | Cellular Component | transcription factor complex |
| GO:0003677 | Molecular Function | DNA binding |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 459 aa
Download sequence Send
to blast |
MSGFARAPNR QAPPATAANG GGGGSQILPP LRRHLAFEST KPQPFPPDNY HRFXGGPRRA 60
GDQEPEAILV RSPVISYSXS LTSKVVLLKI YCKLVQLTQK DNNEVGYSDW TSSPGNTNVI 120
QSPLQTPVSA KGGXVNNRSK ASKGGXSGPQ TPVSIVGLLT KKFINLIKRA EDGILDLNKA 180
AETLEVQKRR IYDITNVLEG IGLIEKKLKN RIRWKGFDAS MPGELDGDLS ILQAEVENLS 240
LQEXRLDDRI RWLFVTEDDI KGLPCFHNET LIAIKAPHGT TLEVPDPDEA VDYPQRRYRI 300
ILRSTMGPID VYLVSQFEEK FEDVHGAEPP VNFPIASGSG SNEHXTTEVV TVESSGKEIE 360
PWLQQVHHTC SDMNASQEFA GGMMKIVPSD VDNDADYWLL SDAEVSITDM WRTDSGVGWN 420
GTDILHADFG VTDVXTSRPQ TPPSRVVEVP SHAVNFTQR
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. |
| Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
| Functional Description ? help
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| Source |
Description |
| UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
