PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Lus10016972 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
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Family | E2F/DP | ||||||||
Protein Properties | Length: 473aa MW: 52219.5 Da PI: 4.9089 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 87.4 | 1e-27 | 145 | 210 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++ +e+gi++ln++a++L dv ++RRiYDi+NVLe+++liek+ kn+irwkg Lus10016972 145 RYDSSLGLLTKKFVNLIKDAEDGIIDLNKAAETL---DV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 210 6899******************************...**..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 7.7E-29 | 142 | 212 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.4E-34 | 145 | 210 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.34E-17 | 145 | 208 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 2.6E-24 | 147 | 210 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 8.63E-33 | 223 | 327 | No hit | No description |
CDD | cd14660 | 9.84E-49 | 224 | 327 | No hit | No description |
Pfam | PF16421 | 7.0E-34 | 226 | 325 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 473 aa Download sequence Send to blast |
MSEGAPASSH PPLPSAPSSG PILPPPGRHL AFVSMKPPFV APDDYHRFTS PAASKVADRE 60 AEAIVVGSPV TLKRKLDDNG IESSKWTSSP GKTDASSSTY HTPVSAKGGR TNNKPKSTKG 120 NKSVPRMPML NPGSPSTLTP AGSCRYDSSL GLLTKKFVNL IKDAEDGIID LNKAAETLDV 180 QKRRIYDITN VLEGIGLIEK TLKNRIRWKG VDSSNSGNAD GNYSLLQAEI EKLSLEEQNL 240 DNQIREMQER IRNFSEDENN QKWLFVTEDD IKSLPCFMNE TLIAIKAPHG TTMEVPDPDE 300 AVDYPQRRYR IILRSTMGPI DVYLVSQFEE NLEEANDAGP SSVANASSSC SSVNPQMEMF 360 ATQRTQNAVE PPPVQDVHHM FTDLNPSEDF VRGMMKIFPT DADNELDYWL RSDVADVSIT 420 DMWRTDSSFP DFYPSPSTPP RPLTWNKIQA EFGMADVHTP RPQTPPSRIN VE* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 2e-23 | 132 | 211 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Lus10016972 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_012074348.1 | 0.0 | transcription factor E2FA | ||||
Swissprot | Q9FNY0 | 1e-151 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A067KIS9 | 0.0 | A0A067KIS9_JATCU; Uncharacterized protein | ||||
STRING | Lus10016972 | 0.0 | (Linum usitatissimum) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF1947 | 34 | 90 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-146 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
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Phytozome | Lus10016972 |
Publications ? help Back to Top | |||
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