PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lj2g3v0216910.1

Common Name

LjSTOP1

Organism

Lotus japonicus

Taxonomic ID

34305

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Loteae; Lotus

Family

C2H2

Protein Properties

Length: 510aa MW: 56625.4 Da PI: 6.5919

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Lj2g3v0216910.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21.1	8.5e-07	276	297	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C++Cgk F+r nL+ H+r H Lj2g3v0216910.1 276 FCTICGKGFKRDANLRMHMRGH 297 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.43E-5	274	300	No hit	No description
PROSITE profile	PS50157	12.03	275	302	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0026	275	297	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	9.3E-6	277	326	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	277	297	IPR007087	Zinc finger, C2H2
SMART	SM00355	110	324	357	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	20	362	384	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 510 aa Download sequence Send to blast
MDSKGSLRAT TWAKSSSLTT SAENGLQTNI SSADSFSLPG FGSLHNQHKW PDPSISDYGV 60 REEAPLQGFS QPSQAQTLLP CDTNNKIKIP DQENCPLSES SQTNRLQNWD PSVMLYNLSF 120 LENKIHELQD LVHLIVSQKD QPNEIVTQEQ QLITTDLTSI IVQLISTAGS LLPSVRQTLI 180 NGNPLVGQLG QLCGIAVPSG SGPSSSCIQP QNNNGNKLSD QSMQNDLPSN REMEQNYMEE 240 HEYKDEDADD GDNLPPGSYE ILQLEKEEIL APHAHFCTIC GKGFKRDANL RMHMRGHGDE 300 YKTPAALAKP HKESGSQPKL IKRYSCPYHG CKRNKDHKKF LPLKTILCVK NHYKRTHCDK 360 SYTCSRCNTK KFSVLADLKT HEKHCGKDKW LCSCGTTFSR KDKLFGHIAL FQGHTPAIPL 420 DESKENNKVG GMNSCLVSNP STENGVQNIM DARANIDDPI SYLSSLNFEA NFGAFNEFTR 480 PPPEESESSF SFFMPGSFKP GGESSRDNIL

Sequence ? help Back to Top

Protein Sequence Length: 510 aa Download sequence Send to blast

MDSKGSLRAT TWAKSSSLTT SAENGLQTNI SSADSFSLPG FGSLHNQHKW PDPSISDYGV  60
REEAPLQGFS QPSQAQTLLP CDTNNKIKIP DQENCPLSES SQTNRLQNWD PSVMLYNLSF  120
LENKIHELQD LVHLIVSQKD QPNEIVTQEQ QLITTDLTSI IVQLISTAGS LLPSVRQTLI  180
NGNPLVGQLG QLCGIAVPSG SGPSSSCIQP QNNNGNKLSD QSMQNDLPSN REMEQNYMEE  240
HEYKDEDADD GDNLPPGSYE ILQLEKEEIL APHAHFCTIC GKGFKRDANL RMHMRGHGDE  300
YKTPAALAKP HKESGSQPKL IKRYSCPYHG CKRNKDHKKF LPLKTILCVK NHYKRTHCDK  360
SYTCSRCNTK KFSVLADLKT HEKHCGKDKW LCSCGTTFSR KDKLFGHIAL FQGHTPAIPL  420
DESKENNKVG GMNSCLVSNP STENGVQNIM DARANIDDPI SYLSSLNFEA NFGAFNEFTR  480
PPPEESESSF SFFMPGSFKP GGESSRDNIL

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots (e.g. root tips and lateral roots), leaves, flowers (e.g. stigma, sepal, anther, and filament), stems, siliques and cotyledons. {ECO:0000269\|PubMed:23935008}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Lj2g3v0216910.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB811782	0.0	AB811782.1 Lotus japonicus LjSTOP1 mRNA for STOP1-like protein, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027346301.1	0.0	protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like isoform X1
Swissprot	Q9C8N5	1e-168	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	S6BUC5	0.0	S6BUC5_LOTJA; STOP1-like protein
STRING	GLYMA16G27280.1	0.0	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5340	32	54

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	1e-163	C2H2 family protein

Publications ? help Back to Top
Ohyama Y, et al. Characterization of AtSTOP1 orthologous genes in tobacco and other plant species. Plant Physiol., 2013. 162(4): p. 1937-46 [PMID:23749850] Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]