PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KHN19914.1
Organism
Glycine soja
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family E2F/DP
Protein Properties Length: 379aa    MW: 41903.7 Da    PI: 4.357
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KHN19914.1genomeTCUHKView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP87.41e-2760125171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                 r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  KHN19914.1  60 RYDSSLGLLTKKFINLIKQAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 125
                 6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.9E-2958127IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.0E-3560125IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.9E-1760123IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023197.6E-2562125IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440741.33E-33139242No hitNo description
CDDcd146601.48E-47140242No hitNo description
PfamPF164216.6E-34141240IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 379 aa     Download sequence    Send to blast
MTPGFTEAAN SPFQTPVSGK TGKGGKSFRL TKGNRLGTQT PGSNIGSPSG NNLTPAGPCR  60
YDSSLGLLTK KFINLIKQAE DGILDLNKAA DTLEVQKRRI YDITNVLEGI GLIEKKLKNR  120
IQWKGLDVSR PGEADDSFPS LQAEVENLTM KERQLDEQIR EMQERLRDLS EDENNDKLLF  180
VTEEDIKNLP CFQNETLIAI KAPHGTTLEV PDPDEAVDYP QRRYRIVLRS TMGPIDLYLV  240
SQFEEKFEEI NGVDVAPKLP SSPDGTKHQS TVVPEDRGKD IEVQGQEAPG PSSDFTTSQD  300
FVSGIMKIVP SDVASEADYW LLSDADVSIT DMWRTEPGVE WNELEPLQED YCMTRENTAT  360
PSHPSNVDEV SSAPKSTGG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-2755126274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapKHN19914.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0524550.0BT052455.1 Medicago truncatula clone MTYFD_FE_FF_FG1G-O-10 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006591066.10.0transcription factor E2FB
RefseqXP_028190672.10.0transcription factor E2FB-like
SwissprotQ9FV711e-145E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A0B2QI720.0A0A0B2QI72_GLYSO; Transcription factor E2FB
TrEMBLA0A445I2A90.0A0A445I2A9_GLYSO; Transcription factor E2FB
TrEMBLK7LQ430.0K7LQ43_SOYBN; Uncharacterized protein
STRINGGLYMA11G18401.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-147E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Qi X, et al.
    Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing.
    Nat Commun, 2014. 5: p. 4340
    [PMID:25004933]
  4. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]