PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KHN02830.1

Organism

Glycine soja

Taxonomic ID

3848

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja

Family

E2F/DP

Protein Properties

Length: 401aa MW: 44087.4 Da PI: 4.5518

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KHN02830.1	genome	TCUHK	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	85.2	5.2e-27	81	146	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg KHN02830.1 81 RYDSSLGLLTKKFINLVKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 146 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	4.5E-29	78	148	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	5.3E-17	81	144	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.2E-34	81	146	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.4E-24	83	146	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	3.17E-48	159	263	No hit	No description
SuperFamily	SSF144074	5.49E-33	159	263	No hit	No description
Pfam	PF16421	6.7E-34	162	261	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005667	Cellular Component	transcription factor complex
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 401 aa Download sequence Send to blast
MKRKSGMTDS EGESQAQKWS NSPGYTNVSN VTNNSPFKTP VSAKGGRAQK AKASKEGRSC 60 PPTPMSNAGS PSPLTPASSC RYDSSLGLLT KKFINLVKHA EDGILDLNKA AETLEVQKRR 120 IYDITNVLEG IGLIEKKLKN RIHWKGIESS TSGEVDGDIS VLKAEVEKLS LEEQGLDDQI 180 REMQERLRNL SENENNQKCL FVTEEDIKGL PCFQNETLIA IKAPHGTTLE VPDPEEAVDY 240 PQRRYRIILR STMGPIDVYL ISQFEEKFEE VNGAELPMIP LASSSGSNEQ LMTEMVPAEC 300 SGKELEPQTQ LSSHAFSDLN ASQEFAGGMM KIVPSDVDND ADYWLLSDAD VSITDMWRTD 360 STVDWNGIDM LHPDFGIISR PQSPSSGLAE VPSTGANSIQ K

Sequence ? help Back to Top

Protein Sequence Length: 401 aa Download sequence Send to blast

MKRKSGMTDS EGESQAQKWS NSPGYTNVSN VTNNSPFKTP VSAKGGRAQK AKASKEGRSC  60
PPTPMSNAGS PSPLTPASSC RYDSSLGLLT KKFINLVKHA EDGILDLNKA AETLEVQKRR  120
IYDITNVLEG IGLIEKKLKN RIHWKGIESS TSGEVDGDIS VLKAEVEKLS LEEQGLDDQI  180
REMQERLRNL SENENNQKCL FVTEEDIKGL PCFQNETLIA IKAPHGTTLE VPDPEEAVDY  240
PQRRYRIILR STMGPIDVYL ISQFEEKFEE VNGAELPMIP LASSSGSNEQ LMTEMVPAEC  300
SGKELEPQTQ LSSHAFSDLN ASQEFAGGMM KIVPSDVDND ADYWLLSDAD VSITDMWRTD  360
STVDWNGIDM LHPDFGIISR PQSPSSGLAE VPSTGANSIQ K

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	2e-25	76	147	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KHN02830.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT093046	1e-147	BT093046.1 Soybean clone JCVI-FLGm-15I8 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006575291.1	0.0	transcription factor E2FA
Refseq	XP_028211267.1	0.0	transcription factor E2FA-like
Swissprot	Q9FNY0	1e-146	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A0B2P0M7	0.0	A0A0B2P0M7_GLYSO; Transcription factor E2FA
TrEMBL	A0A445LRK3	0.0	A0A445LRK3_GLYSO; Transcription factor E2FA
TrEMBL	I1JGJ7	0.0	I1JGJ7_SOYBN; Uncharacterized protein
STRING	GLYMA02G35850.1	0.0	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1947	34	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-141	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083] Qi X, et al. Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing. Nat Commun, 2014. 5: p. 4340 [PMID:25004933]