PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea

Family

WRKY

Protein Properties

Length: 531aa MW: 57659.3 Da PI: 8.1371

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Itr_sc002013.1_g00001.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	96.4	2e-30	168	227	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+a+d +++++tYeg+Hnh+ Itr_sc002013.1_g00001.1 168 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCADDMSILITTYEGTHNHP 227 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	7.0E-32	154	229	IPR003657	WRKY domain
SuperFamily	SSF118290	1.06E-27	161	229	IPR003657	WRKY domain
PROSITE profile	PS50811	28.461	163	229	IPR003657	WRKY domain
SMART	SM00774	9.1E-37	168	228	IPR003657	WRKY domain
Pfam	PF03106	4.3E-27	169	227	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 531 aa Download sequence Send to blast
MGEVMEENQR LKMYLERIMK DYRTLQMQFQ GMVEKEGEKA AKSDDNTPQI TEESELVSLS 60 LGRASAEMKR EDQNRPVIVC AGKDKMDNED NDQKEGLTLG LDCKFKSLQP NNPSTDNSSD 120 EVKEENGETW PPSKALKTMR SGEDEVSQQN PAKRARVSVR VRCDAPTMND GCQWRKYGQK 180 IAKGNPCPRA YYRCTVAPSC PVRKQVQRCA DDMSILITTY EGTHNHPLPL SATAMASTTS 240 AAASMLMSGS STSATTSMPP GNTTTAATST STTNLNGLNF YLSDTSKPKP FYIPTSSITP 300 TLGHPTIVLD LTSTAPSSSS NLSRIGNLGN FPPRFSSTNL NFSSLESNPL PISWNLGTTQ 360 PYNKPHITQS LTFARQQQQQ QPQDNQILFQ SYLSKNNLNN NNNNPSQSLP QETIAAATKA 420 ITSDPNFQSA LAAALSSIMG TNNGNNGASL NLGIHGLAEK LSQNLKAAAE PFPILSSFSP 480 SPNPNKCSSS LLSRPTTTSS ANPHPGNLMY HLQQTSKSKS SSPGDSRDQI I

Sequence ? help Back to Top

Protein Sequence Length: 531 aa Download sequence Send to blast

MGEVMEENQR LKMYLERIMK DYRTLQMQFQ GMVEKEGEKA AKSDDNTPQI TEESELVSLS  60
LGRASAEMKR EDQNRPVIVC AGKDKMDNED NDQKEGLTLG LDCKFKSLQP NNPSTDNSSD  120
EVKEENGETW PPSKALKTMR SGEDEVSQQN PAKRARVSVR VRCDAPTMND GCQWRKYGQK  180
IAKGNPCPRA YYRCTVAPSC PVRKQVQRCA DDMSILITTY EGTHNHPLPL SATAMASTTS  240
AAASMLMSGS STSATTSMPP GNTTTAATST STTNLNGLNF YLSDTSKPKP FYIPTSSITP  300
TLGHPTIVLD LTSTAPSSSS NLSRIGNLGN FPPRFSSTNL NFSSLESNPL PISWNLGTTQ  360
PYNKPHITQS LTFARQQQQQ QPQDNQILFQ SYLSKNNLNN NNNNPSQSLP QETIAAATKA  420
ITSDPNFQSA LAAALSSIMG TNNGNNGASL NLGIHGLAEK LSQNLKAAAE PFPILSSFSP  480
SPNPNKCSSS LLSRPTTTSS ANPHPGNLMY HLQQTSKSKS SSPGDSRDQI I

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	1e-20	155	229	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019198049.1	0.0	PREDICTED: probable WRKY transcription factor 61 isoform X1
Swissprot	A0A3Q7GFB5	1e-142	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A068V4P5	1e-169	A0A068V4P5_COFCA; Uncharacterized protein
STRING	XP_009616443.1	1e-163	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G18860.1	1e-67	WRKY DNA-binding protein 61

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]