PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea

Family

ERF

Protein Properties

Length: 171aa MW: 18794.3 Da PI: 7.9516

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Itr_sc000793.1_g00001.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	58.6	1.5e-18	10	61	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s y GVr ++ +g+++AeIrd ++ g kr++lg+f ae+Aa a+++a+++++g Itr_sc000793.1_g00001.1 10 SNYIGVRKRP-WGKYAAEIRDSTQSG--KRVWLGTFNNAEDAALAYDQAALAMRG 61 5699****.******55444..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	3.94E-29	10	69	No hit	No description
SuperFamily	SSF54171	1.57E-22	10	71	IPR016177	DNA-binding domain
SMART	SM00380	2.3E-34	11	75	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.3E-30	11	69	IPR001471	AP2/ERF domain
Pfam	PF00847	1.4E-12	11	61	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	21.549	11	69	IPR001471	AP2/ERF domain
PRINTS	PR00367	9.3E-12	12	23	IPR001471	AP2/ERF domain
PRINTS	PR00367	9.3E-12	51	71	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 171 aa Download sequence Send to blast
MEAHTSTKTS NYIGVRKRPW GKYAAEIRDS TQSGKRVWLG TFNNAEDAAL AYDQAALAMR 60 GTSACLNFPP EVVRELLEKV DCKEGMSVAA ALKEKHRKRT RRGKGNSPSC KEAEEEGNNG 120 VLVFEDLGSD LLDELLSVTS SSCMFSPGPV TLADHKEINQ LRLPIADRLK P

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	4e-26	12	72	15	75	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019185294.1	2e-94	PREDICTED: ethylene-responsive transcription factor 15-like
Swissprot	A0A3Q7I5Y9	7e-41	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A1S3ZJ47	6e-51	A0A1S3ZJ47_TOBAC; ethylene-responsive transcription factor 15-like
STRING	XP_009804882.1	1e-50	(Nicotiana sylvestris)
STRING	XP_009609581.1	8e-51	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G31230.1	3e-25	ethylene-responsive element binding factor 15

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]