PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea

Family

ERF

Protein Properties

Length: 225aa MW: 24512.8 Da PI: 5.1851

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Itr_sc000271.1_g00080.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	58.4	1.8e-18	56	105	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr ++ +g+++AeIrd ++ ++ r++lg+f+taeeAa +++a+ +l+g Itr_sc000271.1_g00080.1 56 YRGVRKRP-WGKYAAEIRDS-TR-RSVRVWLGTFDTAEEAALVYDQAAFALHG 105 9*****.******3.22.25***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00380	5.1E-34	55	119	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.879	55	113	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.32E-22	55	115	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	3.4E-29	56	114	IPR001471	AP2/ERF domain
CDD	cd00018	2.45E-27	56	114	No hit	No description
Pfam	PF00847	7.3E-13	56	105	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.0E-10	56	67	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.0E-10	79	95	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 225 aa Download sequence Send to blast
MLLYTVLAEA GGGGGGAISS SSSSSSFLGG GPAEEEEEEE EWSSFSRTTI GGGGAYRGVR 60 KRPWGKYAAE IRDSTRRSVR VWLGTFDTAE EAALVYDQAA FALHGSTAVL NFPAEVVYQS 120 LVELGCGFDD GGSPVLALKR RHCKNSRRSS SMMNKKRINN NNNNNNNNNN NNNNNNNNNN 180 NALKKKKEDD EFKGERVHGE VLVLEDLGAE YLEQLLSISE AKLDN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	5e-27	54	115	13	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP229643	1e-32	KP229643.1 UNVERIFIED: Boehmeria nivea AP2/ERF domain-containing protein-like (ERF20) mRNA, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019191842.1	5e-87	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	2e-46	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A251NZY3	8e-59	A0A251NZY3_PRUPE; Uncharacterized protein
TrEMBL	M5W2C0	1e-58	M5W2C0_PRUPE; Uncharacterized protein
STRING	EMJ07486	2e-59	(Prunus persica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	5e-41	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]