PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.11G180100.1.p
Common NameGLYMA_11G180100, LOC100819817
Organism
Glycine max
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family E2F/DP
Protein Properties Length: 461aa    MW: 50648.6 Da    PI: 4.6021
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.11G180100.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP871.4e-27141206171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                          r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Glyma.11G180100.1.p 141 RYDSSLGLLTKKFINLIKQAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 206
                          6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.6E-29139208IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.0E-35141206IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.94E-17141204IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.0E-24143206IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440741.88E-33220323No hitNo description
CDDcd146601.57E-47221323No hitNo description
PfamPF164219.3E-34222321IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 461 aa     Download sequence    Send to blast
MSASRAPPAG AGASKPPDQI MHSMKRQLPF SSMKPPFVAA GDYHRFAPDQ RHDAAEAIVV  60
KTPQLKRKSE AADFEADSGD RMTPGFTEAA NSPFQTPVSG KTGKGGKSFR LTKGNRLGTQ  120
TPGSNIGSPS GNNLTPAGPC RYDSSLGLLT KKFINLIKQA EDGILDLNKA ADTLEVQKRR  180
IYDITNVLEG IGLIEKKLKN RIQWKGLDVS RPGEADDSFP SLQAEVENLT MKERQLDEQI  240
REMQERLRDL SEDENNDKLL FVTEEDIKNL PCFQNETLIA IKAPHGTTLE VPDPDEAVDY  300
PQRRYRIVLR STMGPIDLYL VSQFEEKFEE INGVDVAPKL PSSPDGTKHQ STVVPEDRGK  360
DIEVQGQEAP GPSSDFTTSQ DFVSGIMKIV PSDVASEADY WLLSDADVSI TDMWRTEPGV  420
EWNELEPLQE DYCMTRENTA TPSHPSNVDE VSSAPKSTGG *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A4e-27136207274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant at the G1/S transition. Lower but constant level in the following phases. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:16514015}.
UniprotTISSUE SPECIFICITY: Expressed in proliferating cells and several differentiated tissues. Detected in inflorescence and shoot apical meristems, cotyledonary vascular tissues, leaf primordia, young leaves, base of trichomes, central cylinder and elongation zone of roots, lateral root primordia, flowers, pistils of immature flowers and pollen grains. {ECO:0000269|PubMed:16514015}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapGlyma.11G180100.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0524550.0BT052455.1 Medicago truncatula clone MTYFD_FE_FF_FG1G-O-10 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006591066.10.0transcription factor E2FB
RefseqXP_028190672.10.0transcription factor E2FB-like
SwissprotQ9FV711e-155E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A445I2A90.0A0A445I2A9_GLYSO; Transcription factor E2FB
TrEMBLK7LQ430.0K7LQ43_SOYBN; Uncharacterized protein
STRINGGLYMA11G18401.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Representative plantOGRP12251749
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-157E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]