PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | GRMZM2G041701_P01 | ||||||||
Common Name | LOC100279729, ZEAMMB73_265177 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
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Family | E2F/DP | ||||||||
Protein Properties | Length: 462aa MW: 50278.2 Da PI: 4.8253 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 82.7 | 3e-26 | 145 | 209 | 1 | 70 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwk 70 r+++sL+llt+kf++ll+++++gi++ln++a+ L +v ++RRiYDi+NVLe+++liek+ kn+irwk GRMZM2G041701_P01 145 RYDNSLGLLTKKFINLLKQAPDGILDLNNAAEVL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWK 209 689*******************************...99..****************************8 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.6E-27 | 143 | 211 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 6.0E-34 | 145 | 210 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 6.53E-18 | 145 | 208 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.1E-23 | 147 | 209 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 3.34E-49 | 220 | 326 | No hit | No description |
SuperFamily | SSF144074 | 2.56E-34 | 222 | 326 | No hit | No description |
Pfam | PF16421 | 5.8E-33 | 225 | 324 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0010090 | Biological Process | trichome morphogenesis | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051302 | Biological Process | regulation of cell division | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 462 aa Download sequence Send to blast |
MSGVGSGRPP AAQKILQSLR PPLSFSTPSR PPFAAPDDYH RFPTPAAATS PAATSGGVGA 60 GAAPPDTVEE GLVIRTPLKR KATSEENAAA DSSSCIITSP MLTPVSAKTV KASKAKAKNS 120 KTGPQTPTSN VGSPLNPPTP VGTCRYDNSL GLLTKKFINL LKQAPDGILD LNNAAEVLEV 180 QKRRIYDITN VLEGIGLIEK TLKNRIRWKA LDDSSVQLDN GISALQAEVE NLSLQEQALD 240 ERISDIREKL RGLTEDENNQ RWLYVTEDDI KGLPSFQNET LIAIKAPHGT TLEVPDPDEA 300 GDYLQRRYRI VLRSTMGPID VYLVSQFDEK FEELGGVATP AKHSNVPRHQ PAEDFNTSYA 360 GQSSTLMGVA HDAQHSQKIP QDPSALHDFG GMTRISPSDV HTDSDYWLLT EGDVSMTDMW 420 KTEQAQWDEM DFLSEDVVTP RAHNQQLVTV DGPHMEVPST DP |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 2e-22 | 137 | 211 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Expression -- UniGene ? help Back to Top | ||||||
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UniGene ID | E-value | Expressed in | ||||
Zm.1249 | 0.0 | meristem| ovary| shoot| tassel |
Expression -- Microarray ? help Back to Top | ||||||
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Source | ID | |||||
Expression Atlas | GRMZM2G041701 |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. | |||||
Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | GRMZM2G041701_P01 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | BT054772 | 0.0 | BT054772.1 Zea mays full-length cDNA clone ZM_BFb0035J13 mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | NP_001146160.1 | 0.0 | transcription factor E2F3 | ||||
Swissprot | Q9FNY0 | 1e-129 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | B7ZZN0 | 0.0 | B7ZZN0_MAIZE; Transcription factor E2F | ||||
TrEMBL | K4JEA3 | 0.0 | K4JEA3_MAIZE; E2F-DP-type transcription factor (Fragment) | ||||
STRING | GRMZM2G041701_P01 | 0.0 | (Zea mays) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Monocots | OGMP625 | 37 | 148 | Representative plant | OGRP1225 | 17 | 49 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-124 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
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Phytozome | GRMZM2G041701_P01 |
Entrez Gene | 100279729 |
Publications ? help Back to Top | |||
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