PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

ERF

Protein Properties

Length: 191aa MW: 20765.3 Da PI: 10.5429

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.365850.2	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	62.5	9.4e-20	14	63	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+W+AeIrdp + +r++lg+f+tae Aa+a++ a+++++g Cucsa.365850.2 14 RYRGVRQRP-WGKWAAEIRDPQ----KaARVWLGTFDTAEAAARAYDGAALRFRG 63 7******.******93....36**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	5.9E-33	14	72	IPR001471	AP2/ERF domain
SMART	SM00380	9.9E-36	14	77	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	25.818	14	71	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.63E-22	14	72	IPR016177	DNA-binding domain
Pfam	PF00847	9.4E-14	14	63	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.2E-12	15	26	IPR001471	AP2/ERF domain
CDD	cd00018	7.54E-19	22	72	No hit	No description
PRINTS	PR00367	3.2E-12	37	53	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 191 aa Download sequence Send to blast
MAAAFSGEDR IRRRYRGVRQ RPWGKWAAEI RDPQKAARVW LGTFDTAEAA ARAYDGAALR 60 FRGSKAKLNF PEFVSVFPPS SLPSATHLAS SPVVVPPQDA IGNYLQYSRL LPNSRETSSQ 120 PVPAFERVLC NSPLVNPSSL VSSSGVSNFP FPLSEQQVRH YLPPENQSQG NGGSSMPFPT 180 GFSYRPPANG *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	3e-23	13	71	4	63	ATERF1
3gcc_A	3e-23	13	71	4	63	ATERF1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator of cell proliferation and axillary bud outgrowth. Involved in maintaining the structure of the shoot apical meristem as well as plastochron and phyllotaxy. Activates several genes involved in cell cycle regulation and dormancy breaking, including CYCD3-3, DPA, and BARD1. Strongly down-regulates DRM1, DRMH1, MARD1 and several genes encoding different types of cell wall-remodeling proteins. {ECO:0000269\|PubMed:23616605}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transiently up-regulated 6 to 15 hours after decapitation. {ECO:0000269\|PubMed:23616605}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN812235	0.0	LN812235.1 Cucumis sativus mRNA for ethylene-responsive transcription factor 114, cultivar Summer Green.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004138542.2	1e-135	PREDICTED: ethylene-responsive transcription factor ERF110-like
Swissprot	Q9FH54	1e-33	EF114_ARATH; Ethylene-responsive transcription factor ERF114
TrEMBL	A0A0A0KBY0	1e-134	A0A0A0KBY0_CUCSA; Uncharacterized protein
TrEMBL	A0A0C7KKK2	1e-134	A0A0C7KKK2_CUCSA; Ethylene-responsive transcription factor 114
STRING	XP_004138542.1	1e-135	(Cucumis sativus)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G50080.1	3e-17	ethylene response factor 110

Link Out ? help Back to Top
Phytozome	Cucsa.365850.2
Entrez Gene	101211577

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kong X, et al. PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis. Cell Rep, 2018. 22(5): p. 1350-1363 [PMID:29386120]