PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.177060.1
Common NameCsa_3G727990
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family WRKY
Protein Properties Length: 281aa    MW: 31573.8 Da    PI: 5.3836
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.177060.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY77.21.9e-24122183159
                     ---SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
            WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
                     +dDg++WrKYGqK++ ++++pr+YYrCt++   +C+++k+v+r +++p  + +tY g+H+++
  Cucsa.177060.1 122 VDDGHAWRKYGQKTILNAKYPRNYYRCTHKydqTCQATKQVQRLQDNPPKFRTTYYGNHTCS 183
                     59***************************99999**************************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.6E-24108183IPR003657WRKY domain
PROSITE profilePS5081120.599117180IPR003657WRKY domain
SuperFamilySSF1182909.81E-24118183IPR003657WRKY domain
SMARTSM007743.1E-36122184IPR003657WRKY domain
PfamPF031062.1E-24123182IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009862Biological Processsystemic acquired resistance, salicylic acid mediated signaling pathway
GO:0009864Biological Processinduced systemic resistance, jasmonic acid mediated signaling pathway
GO:0010200Biological Processresponse to chitin
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0050832Biological Processdefense response to fungus
GO:1900056Biological Processnegative regulation of leaf senescence
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 281 aa     Download sequence    Send to blast
MDCSWPDTTP FDRRKAADEL LRGRELAQQL RAYLQISSTP ASQDLLTRIL SSFSKTLSIL  60
NHRCDSDDIN GSIVDSPEDH GSRKSEESGD SCKSSTPNND RRGCYKRRKS CQSWARESCD  120
LVDDGHAWRK YGQKTILNAK YPRNYYRCTH KYDQTCQATK QVQRLQDNPP KFRTTYYGNH  180
TCSNFLKASD IVLGSSNFDD SCSGVLLSFD TTAAPNFFLP HDPTLVKKEE VVTPDAGSGR  240
DDEAVCSPSD YMSTADDHLS EVFMGSVVDF EDDDLPPFHF *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ir8_A6e-23122182868OsWRKY45
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in senescence, biotic and abiotic stress responses by modulating various phytohormones signaling pathways (By similarity). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Required for the resistance (R) gene Mi-1-mediated resistance to potato aphid (e.g. M.euphorbiae) and root-knot nematode (e.g. M.javanica) (PubMed:21898085). {ECO:0000250|UniProtKB:Q9LY00, ECO:0000250|UniProtKB:Q9SUP6, ECO:0000269|PubMed:21898085}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00408DAPTransfer from AT3G56400Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in response to potato aphid (e.g. M.euphorbiae) infestation and root-knot nematode (e.g. M.javanica) inoculation. Up-regulated by salicylic acid (SA) and suppressed by methyl jasmonate (MeJA). {ECO:0000269|PubMed:21898085}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGU9840210.0GU984021.1 Cucumis sativus WRKY protein (WRKY22) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001267577.10.0probable WRKY transcription factor 70-like
SwissprotK4BIZ92e-42WRK70_SOLLC; WRKY DNA-binding transcription factor 70
TrEMBLA0A0A0LF310.0A0A0A0LF31_CUCSA; WRKY transcription factor
TrEMBLE7CEX00.0E7CEX0_CUCSA; WRKY protein
STRINGXP_004160332.10.0(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19953486
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G56400.13e-42WRKY DNA-binding protein 70
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]