PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

ERF

Protein Properties

Length: 130aa MW: 14323.9 Da PI: 9.883

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.156890.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	66.6	4.9e-21	47	96	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+W+AeIrdp+ + +r++lg+f+tae Aa a+++a+++++g Cucsa.156890.1 47 HYRGVRQRP-WGKWAAEIRDPK----KaARVWLGTFDTAEAAALAYDEAALRFKG 96 7******.******94....45*********************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	1.3E-33	46	105	IPR001471	AP2/ERF domain
SMART	SM00380	1.3E-37	47	110	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	8.5E-23	47	105	IPR016177	DNA-binding domain
Pfam	PF00847	8.1E-15	47	96	IPR001471	AP2/ERF domain
CDD	cd00018	1.68E-19	47	105	No hit	No description
PROSITE profile	PS51032	25.014	47	104	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.6E-12	48	59	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.6E-12	70	86	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 130 aa Download sequence Send to blast
MVSALTQVIT SGSGSGSGSS RSLSVVEEPA ASARGDNEEG VKRESRHYRG VRQRPWGKWA 60 AEIRDPKKAA RVWLGTFDTA EAAALAYDEA ALRFKGTKAK LNFPERLTTP PSYPYAPYHH 120 QDDYQNHRF*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	2e-27	44	109	2	68	ATERF1
3gcc_A	2e-27	44	109	2	68	ATERF1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator of cell proliferation and axillary bud outgrowth. Involved in maintaining the structure of the shoot apical meristem as well as plastochron and phyllotaxy. Activates several genes involved in cell cycle regulation and dormancy breaking, including CYCD3-3, DPA, and BARD1. Strongly down-regulates DRM1, DRMH1, MARD1 and several genes encoding different types of cell wall-remodeling proteins. {ECO:0000269\|PubMed:23616605}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transiently up-regulated 6 to 15 hours after decapitation. {ECO:0000269\|PubMed:23616605}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681814	0.0	LN681814.1 Cucumis melo genomic scaffold, anchoredscaffold00089.
GenBank	LN713256	0.0	LN713256.1 Cucumis melo genomic chromosome, chr_2.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004138017.1	1e-91	PREDICTED: ethylene-responsive transcription factor ERF115
Swissprot	Q9FH54	7e-39	EF114_ARATH; Ethylene-responsive transcription factor ERF114
TrEMBL	A0A0A0LTV8	1e-89	A0A0A0LTV8_CUCSA; Uncharacterized protein
STRING	XP_004167196.1	4e-91	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF985	34	115

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G07310.1	2e-31	ERF family protein

Link Out ? help Back to Top
Phytozome	Cucsa.156890.1

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kong X, et al. PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis. Cell Rep, 2018. 22(5): p. 1350-1363 [PMID:29386120]